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Spectrum: Autism Research News

Tag: fragile X syndrome

November 2017
lab mouse in scientists hand with blue gloves

Selective enzyme block reveals new treatment for fragile X

by  /  14 November 2017

A drug that selectively blocks one form of an enzyme called GSK-3 prevents seizures and improves cognitive deficits in a mouse model of fragile X syndrome.

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magnetic stimulation of human brain

Magnetic stimulation bares imbalance of activity in fragile X brains

by  /  14 November 2017

Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.

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closed eye and wide open eye against sky

Autism may disrupt the body’s circadian clock

by  /  13 November 2017

Sleep problems in autism may stem from the same biological changes that underlie the core features of the condition.

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lab mice

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

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white lab rat

‘Fragile’ behaviors mar studies of popular autism mouse model

by  /  13 November 2017

Researchers should proceed with caution when studying the behavior of one of the most popular mouse models of autism: the fragile X mouse model.

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mouse with a sensor connected to brain

Three autism mouse models marked by defects in same circuit

by  /  8 November 2017

Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.

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Two mice sniffing one another.

Drug boosts social behavior in mice with deletion tied to autism

by  /  1 November 2017

A drug that has shown promise for treating fragile X syndrome may ease features of another condition associated with autism.

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October 2017
Brain scans of boys with fragile X syndrome fall into distinct groupings.

Brain scans reveal subtypes of fragile X syndrome in boys

by  /  30 October 2017

Differences in brain structure may distinguish boys with relatively mild features of fragile X syndrome from those with a severe form of the condition.

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A room with two twin beds. A person sitting in one and a sheep sitting in the other.

Autism in fragile X syndrome tied to seizures, sleep problems

by  /  25 October 2017

In people with fragile X syndrome, autism is often accompanied by seizures, trouble falling or staying asleep and anxiety.

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Week of OctoberOct
2nd
2017

Cannabis candidate; omega add-on; oxytocin control and more

by  /  6 October 2017

A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.

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