A drug that selectively blocks one form of an enzyme called GSK-3 prevents seizures and improves cognitive deficits in a mouse model of fragile X syndrome.
Spectrum: Autism Research News
Tag: fragile X syndrome
Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.
Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.
Researchers should proceed with caution when studying the behavior of one of the most popular mouse models of autism: the fragile X mouse model.
Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.
A drug that has shown promise for treating fragile X syndrome may ease features of another condition associated with autism.
Differences in brain structure may distinguish boys with relatively mild features of fragile X syndrome from those with a severe form of the condition.
In people with fragile X syndrome, autism is often accompanied by seizures, trouble falling or staying asleep and anxiety.
A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.