Fragile X syndrome’s link to autism, explained
Fragile X syndrome is a leading genetic cause of autism. People who have either condition often share certain traits, such as difficulties in social situations.
Fragile X syndrome is a leading genetic cause of autism. People who have either condition often share certain traits, such as difficulties in social situations.
A remote Colombian town is home to the world’s largest cluster of people with fragile X syndrome. Scientists are learning from them — and trying to help.
The protein missing in fragile X syndrome, FMRP, facilitates the production of hundreds of unusually large proteins, some of which are linked to autism.
Looking at the brain as a whole suggests that nudging flawed sets of neurons to collaborate better might alleviate autism traits.
More than half of people on the spectrum have four to five other conditions. Which conditions, and how and when they appear, varies from one autistic person to the next.
Autism and intelligence share genetic variants, researchers grow Neanderthal mini-brains and see overlap with autism, and maternal diabetes is an autism risk factor.
Many people with fragile X syndrome show average rates of protein production, challenging a long-held assumption about the condition.
A checklist for fragile X syndrome could help identify people with the condition in low-resource settings, France unveils a plan for early diagnosis and education of children with autism, and virally inserted ‘bar codes’ help track individual neurons.
A modified version of the genetic engineering tool CRISPR may restore expression of the gene mutated in fragile X syndrome.
A semirural Colombian town called Ricaurte is home to the largest recorded genetic cluster of people with mutations linked to fragile X syndrome.