Mutations that appear in only some of the body’s cells contribute to autism in about 4 percent of people with the condition.
Spectrum: Autism Research News
People with autism aren’t easily surprised, the social camouflage some girls and women with autism use may preclude diagnosis, and autism-related genes are rooted deep in human ancestry.
About 8 percent of non-inherited mutations in people with autism occur in only some of the body’s cells, according to a study of 20,000 people.
We finally have access to whole-genome sequences from people with autism. But before we can properly interpret these data, we need to know what we’re looking for.
Variants of some mitochondrial genes may contribute to autism — in some cases, by teaming up with genes in the nucleus.
Teasing out how genes interact can offer clues to autism’s causes and point to treatment targets.
Whether a gene should be considered a ‘novel candidate’ for autism depends not just on whether it’s been linked to the condition before, but on the strength of that link.