Two new analyses help to explain why mutations to the chromosomal region 16p11.2 can lead to autism, intellectual disability or language difficulties.
Spectrum: Autism Research News
A trove of DNA sequences from 141,456 people — and counting — offers an unparalleled look at genetic variation.
Individuals with mutations in an autism gene called TRIO may have a range of conditions, including intellectual disability and anomalous head size.
People with attention deficit hyperactivity disorder may carry certain rare, harmful mutations in many of the same genes as people with autism.
Finding a mutation linked to autism traits can have life-changing consequences for autistic individuals and their families.
People who have a mutation linked to autism plus a second genetic glitch tend to have more severe symptoms than those with the mutation alone.
Two new online resources help researchers predict how mutations alter protein structure.