Beyond the bench: A conversation with Audrey Brumback
Audrey Brumback riffs about volunteering in Mexico, having a lab next door to her husband’s and why she sometimes cries at work.
Audrey Brumback riffs about volunteering in Mexico, having a lab next door to her husband’s and why she sometimes cries at work.
The algorithm estimates a child’s likelihood of having autism from patterns of co-occurring conditions in electronic health records, outperforming a widely used screening test.
Altered electrical activity in the neurons of mice with a mutated copy of SCN2A may explain the animals’ autism-like social behaviors.
Mounting evidence suggests that autism often involves upsets in homeostatic plasticity, a set of processes neurons use to stabilize their activity. These disruptions result from a range of autism-linked mutations and may help to explain the condition’s famed heterogeneity.
Deleterious mutations in an autism-associated gene can make neurons hyperexcitable, raising the risk of epileptic seizures.
As cannabis prohibition slowly lifts in the United States, scientists and families in the autism community are increasingly turning to the drug and its constituent compounds to ease autism-related difficulties, including seizures and irritability.
Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
Mutations in genes that encode a histone, which gives structure to chromosomes, can lead to developmental delay and congenital anomalies.
Cells with excess UBE3A, an autism-linked protein, have atypical firing properties that can be corrected by limiting the protein’s levels, according to new research.