Calming neurons to quell seizures: Q&A with Gabriele Lignani and Dimitri Kullmann
A new gene therapy approach for epilepsy tamps down neural activity on demand.
A new gene therapy approach for epilepsy tamps down neural activity on demand.
Work in fruit flies has helped Paul decode a neurodevelopmental syndrome in children caused by rare de novo variants in the gene PPFIA3.
The temporary easing of traits that a minority of autistic children are reported to show during or after a fever may stem from a rise in body temperature.
This month’s newsletter explores the pandemic’s effects on autism rates, trends in co-occurring mental health conditions, and the impact of intranasal oxytocin.
The drug quells seizures in children with Dravet syndrome or Lennox-Gastaut syndrome.
Prenatal exposure to topiramate increases a child’s autism odds, according to the study that prompted the inquiry, but experts caution that pregnant people with epilepsy have few other options for controlling seizures.
Neurons with a faulty copy of SETD1A, a gene tied to autism and schizophrenia, show structural abnormalities and altered connectivity patterns.
Some copy number variants may boost a person’s chances of having autism, but to a lesser extent than previously thought.
Developmental delay, intellectual disability and behavioral issues are common among people who have mutations in MYT1L, a gene with strong ties to autism.
Treatments that counteract the effects of an SCN2A mutation in mice increase the animals’ sociability in adulthood, according to a new unpublished study.