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Spectrum: Autism Research News

Tag: epilepsy

October 2023
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

New template streamlines sharing clinical trial results

by  /  31 October 2023

This month’s Going on Trial newsletter explores a new tool for communicating with clinical trial participants and their families, among other drug development news.

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Photograph of a gloved hand pointing to a computer screen that is displaying an image of a mouse brain.

Uncertainty and excitement surround one company’s cell therapy for epilepsy

by  /  5 October 2023

After 10 years of work, Neurona may have the data to quiet its skeptics. But its ongoing clinical trial will be the ultimate test.

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Research image of mutations in mouse cortical neurons.

Mutations in multipurpose gene deal dendrites a double whammy

by  /  4 October 2023

The mutations disrupt protein translation as well as the cell’s skeleton, according to a new study.

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August 2023
Close up of blood vessels shows probe sticking to vessel wall.

Brain-surgery-free probes can record single-neuron activity

by  /  15 August 2023

The new devices, which monitor neural activity from within blood vessels, show long-term stability in rats and could one day deliver electrical stimulation.

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April 2023
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Going on Trial: Serotonin drug; psilocybin phase 2; placebo response data

by  /  28 April 2023

This month’s issue of the Going on Trial newsletter explores why it’s more fun to have a beer with friends than by yourself — and how that informs an ongoing clinical trial for autism.

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March 2023
A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Trofinetide approval for Rett; n-of-1 ASO therapies; cord-blood deals

by  /  30 March 2023

This month’s issue of the Going on Trial newsletter examines personalized therapies for rare conditions, Acadia’s new drug for Rett syndrome and developments in a cord-blood program, among other autism-related drug trial news.

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Research image of cultured neurons.

Cannabis compound rebalances signaling to quell seizures in mice

by  /  22 March 2023

Cannabidiol (CBD) blocks the action of a molecule that drives an overexcitability feedback loop in a rodent model of epilepsy.

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Wearable device records, stimulates single neurons in people on the go

by  /  17 March 2023

The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities.

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January 2023
A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdoses

by  /  25 January 2023

Going on Trial rounds up new developments in autism-related drug trials. This month we’re revisiting decade-old data from a trial of arbaclofen for fragile X syndrome and looking into a new implant-based approach to quelling seizures, among other treatment strategies.

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Lab images of cilia.

Autism and the cell’s antennae

by  /  4 January 2023

Many autism-linked genes are somehow tied to cilia, the tiny hair-like sensors that stud a cell’s surface. But the question remains whether, and how, cilia differences contribute to the condition.

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