Autism and the complete human genome: Q&A with Evan Eichler
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
The experimental compound, called GSK-LSD1, enhances social preferences and reduces repetitive grooming in mice, according to a new study.
The gene, dubbed NHIP, is in a chromosomal region that shows unusually low levels of DNA methylation in placentas from women who gave birth to autistic children.
Inspired by watching her autistic nephew grow up, Croen has also been an advocate for bolstering research and services for autistic adults.
How chemical tags called methyl groups position themselves on genetic sequences may hint at some of the causes of autism.
Many of the genes strongly linked to autism are involved in the remodeling of chromatin, the complex of DNA and proteins that makes up chromosomes. Scientists are just beginning to understand why.
A new spin on the classic CRISPR gene-editing tool can alter the genome’s chemical tags and suppress gene expression for months.
Some neurons activate autism-linked genes when they fire, according to a new study.
Altering a protein linked to Rett syndrome so that it cannot bind to a methylation tag in neurons results in Rett-like traits in mice.
Mutations in the autism-linked gene DNMT3A lead to the behaviors and gene-expression changes seen in different neurodevelopmental conditions.