The findings add to the growing evidence that genes with disparate functions can play similar roles in brain development.
Spectrum: Autism Research News
Zebrafish with mutations in 10 different autism-linked genes show a range of unique and shared phenotypes.
A genetic therapy and an existing drug both restore typical brain size in mice missing DYRK1A, a top autism candidate gene, in the cerebral cortex, a new study shows. The animals typically have smaller brains than controls.
A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.
Parents of children with rare autism-linked mutations are banding together for support and to join forces with scientists, accelerating the pace of research.
Children with mutations in a gene called DYRK1A, a leading autism candidate, have a distinct set of features, including intellectual disability, speech delay, motor problems and a small head.
Families need more support from researchers in order for their heroic efforts to be optimally effective.