Skip to main content

Tag: DYRK1A

July 2021
Illustration shows yellow landscape with blue sections and a lot of trains on paths with kids on the trains, going different directions.
Features / Deep Dive

Mapping the futures of autistic children

by  /  14 July 2021

Researchers can roughly project what autistic children’s lives will look like years down the road. But how good is their crystal ball — and what are its benefits?

0 Comments
April 2021
Two views of mouse brain slices colorized in green and red.
News

Jump-starting growth signaling reverses microcephaly in autism mouse model

by  /  29 April 2021

A genetic therapy and an existing drug both restore typical brain size in mice missing DYRK1A, a top autism candidate gene, in the cerebral cortex, a new study shows. The animals typically have smaller brains than controls.

0 Comments
February 2021
Oil and water with colors behind: blue, green, yellow and red.
Opinion / Q&A

How microscopic ‘condensates’ in cells might contribute to autism

by  /  23 February 2021

A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.

0 Comments
News

Mutations in frogs point to autism genes’ shared role in neurogenesis

by  /  10 February 2021

Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.

0 Comments
April 2019
children playing at a genetic family group meeting
Features / Deep Dive

How families are driving the study of autism genes

by  /  10 April 2019

Parents of children with rare autism-linked mutations are banding together for support and to join forces with scientists, accelerating the pace of research.

0 Comments
October 2017
Grid of 8 portraits of children with characteristic facial features
News

Small head, speech delay characterize mutations in autism gene

by  /  16 October 2017

Children with mutations in a gene called DYRK1A, a leading autism candidate, have a distinct set of features, including intellectual disability, speech delay, motor problems and a small head.

0 Comments
June 2017
Opinion / Viewpoint

Family groups play key role in advancing autism research

by  /  27 June 2017

Families need more support from researchers in order for their heroic efforts to be optimally effective.

0 Comments
Illustration showing large group of people in a shape suggestive of a GWAS visual, connected to a pertri dish. The image is suggestive of large scale genetics research.
Features / Deep Dive

From 0 to 60 in 10 years

by  /  27 June 2017

After a decade of fast-paced discovery, researchers are racing toward bigger datasets, more genes and a deeper understanding of the biology of autism.

0 Comments
February 2017
News

International effort expands list of genes tied to autism

by  /  15 February 2017

A massive sequencing study spanning seven countries links 38 new genes to autism and developmental delay.

2 Comments
August 2015
News

Chromosome 7 flaws alter chemical tags throughout genome

by  /  21 August 2015

Alterations to chromosome 7 lead to changes in the chemical marks that direct gene expression.

1 Comment