Researchers know little about the ways genetic variants affect development in the infant brain. Knickmeyer, who launched the Organization for Imaging Genomics in Infancy, has spent the past five years trying to close the gap.
Spectrum: Autism Research News
Tag: diffusion tensor imaging
Babies who are later diagnosed with autism may show aberrant connections between some brain regions in their first year of life.
Bundles of nerve fibers that bridge brain areas develop rapidly during the first six months of life. Fibers that connect language regions mature more slowly than those linking motor regions.
Children with autism, attention deficit hyperactivity disorder or obsessive-compulsive disorder all show similar disruptions in brain structure.
Unusually thin nerve fibers in the brain may underlie the motor difficulties seen in children with Angelman syndrome, an autism-related condition.
An intricately pleated brain may underlie the highly organized connections between nearby neurons in people with autism.
The brains of young children with autism show abnormally dense connections involving the frontal lobe. The excess wiring may disrupt the development of social and language circuits.
The bundle of nerves that connects the brain’s two hemispheres is abnormally thick in infants who are later diagnosed with autism. The broader the bundle, called the corpus callosum, the more severe a child’s symptoms.
Among babies who go on to receive a diagnosis of autism at age 2, alterations in brain structures forecast the severity of repetitive behaviors. The preliminary results were presented Saturday at the 2015 International Meeting for Autism Research in Salt Lake City, Utah.
Even small movements of the head during magnetic resonance imaging can lead to spurious measurements of brain structures, according to a new study.