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Spectrum: Autism Research News

Tag: cortex

December 2010

Molecular mechanisms: Autism brains have altered neurons

by  /  7 December 2010

Changes in the bodies of neurons may account for communication deficits in the brains of people with autism, according to a study published 3 November in The Journal of Neuroscience.

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Risk gene for autism rewires the brain

by  /  1 December 2010

A variant of the autism risk gene CNTNAP2 may alter the brain to emphasize connections between nearby regions and diminish those between more distant ones, according to a study published 3 November in Science Translational Medicine.

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November 2010

Mapping the mind

by  /  26 November 2010

Chinese researchers have developed a new imaging system, called micro-optical sectioning tomography or MOST, to generate a three-dimensional image of neurons in a whole mouse brain.

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‘Daydreaming’ circuit implicated in autism, attention deficit

by  /  24 November 2010

Areas of the brain that are active when people are daydreaming or sleeping, and quiet when they are engaged in a task, are imperfectly synchronized in people with autism and attention deficit hyperactivity disorder, researchers say.

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Modeling captures mouse habitat’s effect on neurons

by  /  19 November 2010

Computerized three-dimensional modeling shows nerve cell abnormalities in the hippocampus of fragile X mice — and suggests the importance of raising experimental mice in more natural habitats, according to a poster presented Wednesday at the Society for Neuroscience annual meeting in San Diego.

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Genetics: Two families link new gene to autism

by  /  15 November 2010

Researchers have narrowed down a genetic region associated with autism to one protein, cadherin 8, that helps bind cells together, according to a study published online in October in the Journal of Medical Genetics. This is the first time CDH8, the gene that encodes this protein, has been associated with autism.

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October 2010

Estrogen reverses autism-like features in mice

by  /  4 October 2010

Two new studies provide clues that may explain sex differences in autism prevalence. Italian researchers have found that injecting estrogen into the brains of young male mice reverses some of the structural and behavioral changes associated with low levels of reelin — a brain protein that has been previously implicated in autism — and the effects endure into adulthood.

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September 2010

Genetics: Postmortem study links new gene to autism

by  /  27 September 2010

A study of postmortem brain tissue shows that RPP25, a gene on the autism-linked 15q22-26 chromosomal region, is expressed differently in the brains of people with the disorder. This is the first time this gene has been implicated in autism.

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July 2010

Scientists flash videos of brain development in fragile X

by  /  30 July 2010

Scientists have for the first time captured a dynamic picture of brain defects in young mouse models of fragile X syndrome. The findings appeared in June in the Journal of Neuroscience.

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Study finds weak genetic link between autism and intelligence

by  /  20 July 2010

Autism and intellectual disability often occur together, but in most cases that overlap is not genetic, according to a study of twin pairs published in the American Journal of Medical Genetics. Unraveling this link might help researchers pinpoint brain circuits involved in both conditions, and better understand the diversity of symptoms in the autism spectrum, experts say.

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