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Spectrum: Autism Research News

Tag: cortex

August 2011

Language gene regulates autism candidate

by  /  25 August 2011

A protein linked to language development, FOXP2, regulates the autism candidate gene MET, according to a study published 10 August in the Journal of Neuroscience.

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July 2011

Brains of toddlers with autism out of sync

by  /  11 July 2011

Many toddlers with autism have weak connections between the two sides of the brain, according to the first-ever analysis of brain connections in young children with the disorder, published 23 June in Neuron.

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Cognition and behavior: Brain overgrowth in autism ends early

by  /  1 July 2011

The rapid brain growth seen in children with autism occurs early in life, before children reach 2 years of age, according to a study published in the May issue of Archives of General Psychiatry.

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June 2011

Molecular mechanisms: Mouse model supports role for SHANK3 in autism

by  /  3 June 2011

Mice with a mutation in SHANK3, a leading autism candidate gene, show moderate social defects, including less-than-normal interest in other mice. The findings, published 27 May in Cell, suggest that mutations in different sites on the gene can lead to different behaviors. This paper was retracted on 17 January 2013. Associate director of research Alan Packer discusses the implications of the retraction here.

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May 2011

Networks of genes altered in autism brains, study says

by  /  25 May 2011

Two networks of genes are abnormally expressed in the brains of people with autism, according to a study published today in Nature.

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Rett protein alters visual circuits in mice

by  /  23 May 2011

MeCP2, the protein that’s missing or mutated in Rett syndrome, is crucial for remodeling neural circuits in response to vision, according to a study published in April in Neuron.

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Brain photos reveal multiple responses to single scene

by  /  11 May 2011

The brain collects information on an object’s orientation, direction and speed all at the same time, according to a study published 15 April in NeuroImage.

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April 2011

Molecular mechanisms: Mice lacking MET have strong brain connections

by  /  26 April 2011

Mice missing the autism candidate gene MET have connections in the cortex that are twice as strong as those in controls, according to a new study.

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Specialized neurons help explore circuit defects in autism

by  /  14 April 2011

A powerful cell that dampens electrical signaling in the brain could help unravel the disrupted brain wiring seen in people with autism, according to results presented yesterday at the Wiring the Brain meeting in Ireland.

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Imaging biomarkers could signal autism spectrum disorder

by  /  12 April 2011

There does not appear to be a single genetic or environmental cause of autism, and given the heterogeneity of symptoms, coming up with a clear yes or no test for autism is challenging. Timothy Roberts argues that imaging and electrophysiology are key in the search for autism biomarkers.

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