‘Mini-brains’ created in a dish may reveal autism’s roots and point to treatments, but they do not yet mirror some critical features of a human brain.
Spectrum: Autism Research News
The brains of some women with autism more closely resemble those of typical men than those of typical women.
The brains of people with autism show a distinct molecular signature that reflects alterations in how genes are pieced together and expressed.
The brains of many people with autism may exhibit a characteristic arrangement of chemical groups on the proteins that DNA coils around.
Patterns of activity in certain brain regions may predict how well a child with autism will respond to a behavioral therapy.
Lowering the levels of OTX2, a protein found in the fluid that bathes the brain, prevents many abnormal behaviors in mouse models of Rett syndrome.
Gene expression in so-called ‘organoids’ resembles the pattern seen in the first few weeks of a developing brain.