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Spectrum: Autism Research News

Tag: corpus callosum

May 2013

Lack of corpus callosum yields insights into autism

by  /  2 May 2013

A rare birth defect offers a unique perspective on the connectivity theory of autism. Up to one-third of those missing all or part of the corpus callosum, a thick tract of nerve fibers connecting the left and right brain hemispheres, meet the diagnostic criteria for autism, several recent studies suggest.

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April 2013

Siblings of children with autism see and hear differently

by  /  18 April 2013

Three new studies published in March suggest that some infants who have a high risk of developing autism show early differences in brain responses to sight and sound.

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March 2013

Is ‘underconnectivity’ in autism specific to frontal cortex?

by ,  /  22 March 2013

Autism may result from reduced anatomical connectivity and functional connectivity between the frontal cortex and more posterior areas of the brain, say Marcel Adam Just and Timothy Keller.

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February 2013

Genetics: Study pinpoints autism gene on chromosome 1

by  /  6 February 2013

Deletion of CHRM3, a gene on chromosome 1, leads to autism-like behaviors, according to a case study published 16 December in the European Journal of Medical Genetics.

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January 2013

Cognition and behavior: Symmetry skewed in autism brains

by  /  30 January 2013

Teenagers with autism have an atypical balance between the right and left sides of the corpus callosum, which connects the two hemispheres of the brain, according to a study published 23 November in the Journal of Autism and Developmental Disorders.

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November 2012

Molecular mechanisms: Autism gene regulates brain structure

by  /  30 November 2012

Loss of one copy of TBR1, an autism-linked gene involved in fetal brain development, leads to brain malformations, according to a study published in the September issue of Molecular Syndromology.

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Cognition and behavior: Corpus callosum disrupted in autism

by  /  27 November 2012

Nearly half of children with malformation of the corpus callosum, which links the two hemispheres of the brain, have symptoms of autism, according to a study published 5 October in the Journal of Autism and Developmental Disorders.

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October 2012

Mice with autism-linked deletion show unexpected deficits

by  /  15 October 2012

Mice lacking one copy of the autism-linked 16p11.2 chromosomal region are thin, deaf and show repetitive behaviors. They also have altered proportions of neurons in their brains, particularly those that express the chemical messenger dopamine. The unpublished results were presented Sunday at the 2012 Society for Neuroscience annual meeting in New Orleans.

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September 2012

Autism risk gene found to alter brain wiring

by  /  13 September 2012

MET, a leading candidate gene for autism risk, influences the strength of connections between brain regions involved in social behaviors, and this effect is especially prominent in people with the disorder. The findings are from a large study using several imaging techniques, published 6 September in Neuron.

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August 2012

Genetics: FOXG1 mutations underlie atypical Rett syndrome

by  /  14 August 2012

Seven individuals who have the symptoms of Rett syndrome carry a genetic disruption near, or overlapping with, the FOXG1 gene, according to a report published 27 June in the European Journal of Human Genetics.

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