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Spectrum: Autism Research News

Tag: connectivity theory

March 2013

Fixing motion

by  /  22 March 2013

New methods to deal with motion artifacts in brain imaging data are critically important, says Mike Tyszka.


How do we connect the dots of connectivity?

22 March 2013

Growing evidence suggests that abnormal connectivity in the brain underlies autism, but conflicting interpretations persist about where and how the dysfunction occurs. How do we investigate the underlying mechanisms of this theory?


Six questions for connectivity theory research

by  /  22 March 2013

‘Underconnectivity’ is considered one of the best-supported theories for the neural basis of autism. But many questions remain unanswered, says Jon Brock.


Local connections

by  /  22 March 2013

To better understand how local connectivity is altered in autism, we first need to define what it means, says Tal Kenet.


Negative results

by  /  22 March 2013

A number of studies have found no connectivity differences between people with autism and controls, but few have been published so far, says Dan Kennedy.


Is ‘underconnectivity’ in autism specific to frontal cortex?

by ,  /  22 March 2013

Autism may result from reduced anatomical connectivity and functional connectivity between the frontal cortex and more posterior areas of the brain, say Marcel Adam Just and Timothy Keller.


Researchers peer into fetal brains, map connectivity

by  /  20 March 2013

Researchers can use functional magnetic resonance imaging to map fetal brain connectivity during the second and third trimesters of pregnancy, according to a study published 20 February in Science Translational Medicine.

February 2013

The 2003 paper proposing signaling imbalance in autism

by ,  /  26 February 2013

In 2003, John Rubenstein and Michael Merzenich first described the theory, now popular in autism, that the disorder reflects an imbalance between excitation and inhibition in the brain. Takao K. Hensch and Parizad M. Bilimoria review the paper and its impact on the field.


Autism brains marked by weak local connections, study says

by  /  21 February 2013

Connections between neighboring groups of brain cells are weaker in individuals with autism than in controls, according to a report published 14 January in the Proceedings of the National Academy of Sciences.

October 2012

Robotic tool profiles patterns of neurons

by  /  19 October 2012

Researchers have launched a $4.3 million five-year collaborative effort to profile thousands of types of neurons in the brain, detailing their shape, signaling patterns and gene expression. The project was presented in a poster session Tuesday at the 2012 Society for Neuroscience annual meeting in New Orleans.