Three studies published over the past two months have found significant evidence that children and adolescents with autism have brains that are overly connected compared with the brains of controls. The findings complicate the theory that autism is fundamentally characterized by weakly connected brain regions.
Spectrum: Autism Research News
Tag: connectivity theory
Studies at the level of neural circuits are needed to better understand the importance of both increased and decreased connectivity between different regions in the autism brain, say John Rubenstein and Vikaas Sohal.
A large, multisite dataset of brain scans identifies autism with 60 percent accuracy, much lower than the numbers cited by single-site studies. The study, published 25 September in Frontiers in Human Neuroscience, highlights the vast differences in equipment, quality and methods across sites.
Emerging findings in children with autism are showing both hyperconnectivity and underconnectivity in different regions and circuits throughout the brain.
Elliott Sherr is unraveling the effects of genetics and brain structure in a handful of disparate disorders that each illuminates some aspect of autism.
A technique borrowed from geography bolsters the idea that altered wiring in the brain’s gray matter plays a role in autism, according to a report published 22 July in the Proceedings of the National Academy of Sciences.
A new database that houses brain scans from 17 labs worldwide will allow scientists to study brain connectivity and function in autism. Researchers debuted the new resource’s power in a study published 18 June in Molecular Psychiatry.
Advanced imaging techniques may reveal more precise pictures of how of the brain’s regions communicate with one another. How much of the neurodevelopmental riddle of autism lies in these tracts?
New techniques to scan the brain can produce exquisitely detailed views of white matter, which contains the long cellular fibers that connect neurons. Many of the advances are emerging from the Human Connectome Project, a five-year push to map the brain’s wiring.
A strain of mice with autism-like behaviors is missing a corpus callosum, a bundle of nerve fibers that connects the two hemispheres of the brain. Two studies published this month investigate the link between these two features.