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Tag: CNTNAP2

March 2020
microscopic views of proteins
News

Alzheimer’s protein turns up as potential target for autism treatments

by  /  2 March 2020

Lowering the levels of a protein called tau, best known for its involvement in Alzheimer’s disease, improves behavior in two mouse models of autism.

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December 2019
Mouse sniffing the air
News

Mice with autism mutation may be indifferent to social scents

by  /  5 December 2019

Neurons in mice that lack an autism gene called CNTNAP2 do not differentiate well between social and nonsocial smells — an issue that seems to stem from haphazard neuronal firing.

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October 2019
News

Transplanted neurons rescue social behavior but not brain circuits

by  /  20 October 2019

Injecting cells called interneurons into the brains of a mouse model of autism restores typical social behavior. But the reason for this effect is a puzzle.

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News

Skew in neuron numbers may explain sensory sensitivity in autism

by  /  20 October 2019

Loss of certain neurons on one side of the brain may explain why some autistic people are hypersensitive to touch.

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News

Nobel predictions: Autism research may win big this year

by  /  4 October 2019

Forecasts for this year’s Nobel Prizes include several researchers whose work is relevant to autism.

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February 2019
Close up of mouse shows whiskers
News

Four sets of mice call popular autism theory into question

by  /  25 February 2019

An analysis of four mouse models negates certain assumptions underlying the signaling imbalance theory of autism.

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News

Brain’s prefrontal cortex conducts symphony of social players

by  /  20 February 2019

A brain region that orchestrates responses to social cues and aids decision-making may be off tempo in autism.

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December 2018
Siblings, a baby and a toddler, play together at home.
Features / Deep Dive

How pregnancy may shape a child’s autism

by  /  5 December 2018

Autism is predominantly genetic in origin, but a growing list of prenatal exposures for mother and baby may sway the odds.

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November 2018
Delicate network of neurons and synapses.
News

Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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October 2018
Illustration of human brain in brackets suggesting circuit alterations that is associated with certain genetic mutations.
Opinion / Viewpoint

Brain scans of sleeping mice hint at subtypes of autism

by  /  9 October 2018

Mapping the effects of autism mutations on mouse brain circuits may reveal subtypes of the condition in people.

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