Tag: CNTNAP2

October 2019
News

Transplanted neurons rescue social behavior but not brain circuits

by  /  20 October 2019

Injecting cells called interneurons into the brains of a mouse model of autism restores typical social behavior. But the reason for this effect is a puzzle.

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News

Skew in neuron numbers may explain sensory sensitivity in autism

by  /  20 October 2019

Loss of certain neurons on one side of the brain may explain why some autistic people are hypersensitive to touch.

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News

Nobel predictions: Autism research may win big this year

by  /  4 October 2019

Forecasts for this year’s Nobel Prizes include several researchers whose work is relevant to autism.

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February 2019
Close up of mouse shows whiskers
News

Four sets of mice call popular autism theory into question

by  /  25 February 2019

An analysis of four mouse models negates certain assumptions underlying the signaling imbalance theory of autism.

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News

Brain’s prefrontal cortex conducts symphony of social players

by  /  20 February 2019

A brain region that orchestrates responses to social cues and aids decision-making may be off tempo in autism.

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December 2018
Siblings, a baby and a toddler, play together at home.
Features / Deep Dive

How pregnancy may shape a child’s autism

by  /  5 December 2018

Autism is predominantly genetic in origin, but a growing list of prenatal exposures for mother and baby may sway the odds.

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November 2018
Delicate network of neurons and synapses.
News

Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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October 2018
Illustration of human brain in brackets suggesting circuit alterations that is associated with certain genetic mutations.
Opinion / Viewpoint

Brain scans of sleeping mice hint at subtypes of autism

by  /  9 October 2018

Mapping the effects of autism mutations on mouse brain circuits may reveal subtypes of the condition in people.

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May 2018
News

Monkey study bolsters case for brain hormone’s role in autism

by  /  29 May 2018

Male monkeys that avoid touching, grooming or playing with others have low brain levels of the hormone vasopressin.

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April 2018
CASPR2 antibodies (green) bind to sensory neurons that send signals to the spinal cord (right) but not to neurons in the spinal cord (left).
News

Loss of autism gene makes mice sensitive to pain

by  /  9 April 2018

Mice lacking CNTNAP2, a gene strongly linked to autism, are acutely sensitive to pain.

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