Skip to main content

Spectrum: Autism Research News

Tag: clinical trials

February 2023
Picture of a caged mouse with an EEG implanted.

Adult Angelman mice get some benefit from boosting UBE3A gene expression

by  /  9 February 2023

The treatment eases the animals’ sleep troubles, suggesting it has clinically meaningful effects beyond what was thought to be a critical window in early life.

Comments
January 2023
A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdoses

by  /  25 January 2023

Going on Trial rounds up new developments in autism-related drug trials. This month we’re revisiting decade-old data from a trial of arbaclofen for fragile X syndrome and looking into a new implant-based approach to quelling seizures, among other treatment strategies.

Comments
Illustration of a signature being signed on a form.

Decisional capacity and informed consent, explained

by  /  23 January 2023

To include more autistic people in research, here’s what scientists need to know about informed consent procedures for study participants who have impaired decision-making capacity.

Comments
A woman sits and works at a laptop while her daughter sits next to her and looks out of a glass door.

New tool aims to capture full breadth of repetitive behaviors

by  /  13 January 2023

The measure breaks the behaviors down into eight distinct subdomains — categorization that could prove useful for clinical trials, its creator says.

Comments
October 2022
Jeremy Levin, chief executive officer of Ovid Therapeutics, stands against a bench in a lab.

What next for Angelman?

by  /  20 October 2022

A meeting in Texas reckons with the future of treatment, following two setbacks in 2020.

Comments
Photograph of a mouse nesting in a pile of hay.

Scoring mouse behaviors: Q&A with Michael Sidorov

by  /  17 October 2022

A new analysis package enables researchers to distill multiple measures of Angelman syndrome mice into a single ‘severity score.’

Comments
An illustration of a scientist sitting at a desk with abstract shapes representing ideas floating above her.

Designing autism-friendly trials: Q&A with Caroline Averius and Zachary Williams

by  /  7 October 2022

The pair’s new guidebook offers practical steps to make clinical trials easier and more meaningful for autistic participants.

Comments
Laura Cancedda in Iama's lab.

Building a better drug

by  /  6 October 2022

Iama Therapeutics is hoping a new class of molecule will prove successful against an old target in autism.

Comments
A woman in a lab coat types at a computer.

New diagnostic code for PTEN syndrome may spur research

by  /  3 October 2022

The code may help scientists identify people with the autism-linked condition and recruit them into clinical trials.

Comments
September 2022

Oxytocin lessons from autism-linked syndromes: A chat with Christian Schaaf and Ferdinand Althammer

by  /  7 September 2022

Oxytocin therapies have failed to consistently benefit autistic people, but their effects in people with two autism-linked conditions may yield new insights, experts argue.

Comments