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Spectrum: Autism Research News

Tag: CHD8

May 2019
Toddler having head measured at clinic

With its targets, top autism gene may define a form of the condition

by  /  3 May 2019

Children with mutations either in CHD8 — a top autism gene — or in genes that CHD8 controls share similar characteristics.

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November 2018
white mouse in a man's hands, closeup.

Mouse, human ‘co-clinical’ trials could speed autism drug discovery

by  /  8 November 2018

A team of researchers is trialing a fast approach to autism drug development: simultaneously testing candidates in people and in mice.

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Neurons glow green in mice brain.

Loss of autism gene alters landscape of inhibitory brain signals

by  /  6 November 2018

Mice lacking one copy of a leading autism gene have hyperexcitable brains and problems with learning and memory.

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October 2018
A boy toddler learns to walk with an adult holding his hands.

Some ‘autism genes’ show stronger ties to related conditions

by  /  17 October 2018

The largest autism sequencing study to date implicates 99 genes in the condition — but nearly half have a tighter link to intellectual disability or developmental delay.

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June 2018

Mice missing top autism gene have overconnected brains

by  /  11 June 2018

Mice with one inactivated copy of CHD8, a top autism gene, show an unusually high degree of synchrony in neural activity between brain regions.

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Growth spurt in head, skeleton mark autism in boys

by  /  6 June 2018

Boys with autism have smaller heads, are shorter and weigh less at birth than typical children do — but all that changes by age 3.

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March 2018
Mouse in a lab or maze hops around sniffing here and there

Why studying autism in mice may be doomed to fail

by  /  21 March 2018

After more than a decade of effort, scientists are questioning whether mouse models of autism can ever capture the social deficits seen in people with the condition.

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How to improve mouse models’ usefulness for understanding autism

by  /  20 March 2018

Integrating human-specific genetic elements into mice may provide a permissive, ‘humanized’ environment for studying autism.

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January 2018
three mice with one in the spotlight

‘Retired’ mice find new life as top models for autism

by  /  25 January 2018

As the list of autism candidate genes grows, some mouse models of the genes turn up in long-forgotten studies.

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Week of JanuaryJan
8th
2018

Ratio reversal; gender bender; ad accusations and more

by  /  12 January 2018

The male-dominated sex bias in autism is reversed in a related syndrome, a researcher’s gender could influence her study’s outcome, and an award-nominated ad featuring a young man with autism draws criticism.

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