An expanding collection of websites compiles up-to-date information on the characteristics of people with mutations in genes linked to autism and other conditions.
Spectrum: Autism Research News
Mutations in CHD8 lead to brain overgrowth or undergrowth in mice, depending on how they affect the gene’s expression.
A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.
Many people with mutations in the NCKAP1 gene have autism or autism traits, according to a new study spanning seven countries.
People with mutations in CHD8, a top autism gene, tend to be tall and have large heads.
Mice missing a copy of CHD8, a top autism gene, show a signaling imbalance in their brains — a finding in line with a popular hypothesis about autism’s origins.
Children with autism who carry mutations in the chromosomal region 16p11.2 or the gene CHD8 — two of the leading risk factors for autism — show distinct patterns of chemical tags on their DNA.