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Spectrum: Autism Research News

Tag: cerebellum

November 2022
Three-dimensional structure of cells in the cerebellum.

Flexible genomic architecture undergoes major redesigns during cerebellum development

by  /  13 November 2022

A new atlas reveals how the structural shake-ups within a cell’s genome differ by cell type and brain region over time.

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September 2022
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Brain aging, oxytocin pathways, biomarker back-up

by  /  15 September 2022

Null and replicated results in this month’s newsletter tackle aging, a purported pathway for oxytocin’s effects on autistic people, and a possible autism biomarker.

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July 2022

Mouse study links dopamine in cerebellum to social behavior

by  /  6 July 2022

The signaling molecule’s social role in the ‘little brain’ involves Purkinje neurons in the Crus I and Crus II regions, a new study reveals.

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June 2022
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: INSAR keynote, typical cerebellums, social subdomains

by  /  9 June 2022

In this edition, researchers sink a purported link between cerebellar volume and autism and buoy a theory about measuring social behaviors.

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May 2022
White lab mice bunched up in corner of cage.

Mouse models mirror cerebellum patterns seen in autism

by  /  12 May 2022

Animals with different autism-linked mutations share disruptions to the mTOR signaling pathway, pointing to a potential molecular mechanism for the atypical cerebellar development seen in some autistic people.

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April 2022

Mice missing key clock gene show autism-like traits

by  /  28 April 2022

A new study is the first to link social, repetitive and motor behaviors to mutations in BMAL1, which regulates the body’s circadian rhythms.

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March 2022

Autism model mice develop typical social and motor behaviors after drug treatment

by  /  9 March 2022

The drug suppresses an overactive signaling pathway implicated in tuberous sclerosis complex.

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February 2022

Cerebellum size shows tenuous genetic link to autism

by  /  21 February 2022

Some genomic areas that help determine cerebellar size are associated with autism, schizophrenia and bipolar disorder, according to a new study. But heritable variants across the genome that also influence cerebellar size are not.

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September 2021

Placental hormone loss spurs autism-like traits in mice

by  /  2 September 2021

Mice exposed to unusually low levels of the placental hormone allopregnanolone in the womb show atypical brain development and autism-like behaviors.

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August 2021

Molecular overlap links tuberous sclerosis, fragile X

by  /  16 August 2021

Brain cells from the cerebellums of mice that model tuberous sclerosis show dampened levels of proteins controlled by FMRP, the protein missing in fragile X syndrome.

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