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Tag: cell adhesion

March 2011

Genetics: Autism language gene affects general population

by  /  8 March 2011

Genetic risk factors for specific language impairment and autism affect the timing of language learning in the general population, according to a study published in February in Genes, Brain and Behavior.

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November 2010

Genetics: Two families link new gene to autism

by  /  15 November 2010

Researchers have narrowed down a genetic region associated with autism to one protein, cadherin 8, that helps bind cells together, according to a study published online in October in the Journal of Medical Genetics. This is the first time CDH8, the gene that encodes this protein, has been associated with autism.

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October 2010

Cancer protein directs synapse formation, study shows

by  /  21 October 2010

A tumor suppressor best known for its role in colorectal cancer plays a critical role in forming connections between neurons, according to a study in the August 18 issue of the Journal of Neuroscience.

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July 2010

Synaptic defects link autism, schizophrenia

by  /  2 July 2010

Several independent groups have found previously unknown risk genes for autism, schizophrenia and mental retardation. The candidate genes have one thing in common: they encode proteins that are needed for the healthy function of synapses, the junctions between neurons.

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May 2010

Study implicates cell-adhesion proteins in autism

by  /  18 May 2010

Variations in two genes needed to form connections between brain cells may be associated with autism spectrum disorder, according to a study published 25 March in Molecular Autism. Some variants in the genes seem to increase susceptibility to autism, whereas others protect children from developing the disorder.

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Mouse models reveal workings of neuroligin-1

by  /  4 May 2010

Researchers are tinkering with mouse models to investigate the function of a protein that helps wire neurons together and that has repeatedly been linked to autism. Three such reports of the protein, neuroligin-1, have appeared this year.

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February 2010

Dog pedigrees unearth genes for psychiatric disease

by  /  22 February 2010

Researchers are using dogs as models of psychiatric and behavioral conditions, including obsessive-compulsive disorder and autism.

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November 2009

Massive genomics project unveils schizophrenia results

by  /  10 November 2009

The Psychiatric GWAS Consortium has released its first batch of analyses, identifying several significant common variations associated with schizophrenia. The results were presented Sunday at the World Congress of Psychiatric Genetics in San Diego.

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November 2008

Finding the right (synaptic) partners

by  /  19 November 2008

Researchers are narrowing in on a pool of genes that may be involved in helping neurons find their targets, according to unpublished work presented today in a poster session at the Society for Neuroscience meeting.

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