Mice with mutations in the autism-linked gene WDFY3 have enlarged brains reminiscent of those seen in some children with autism, according to a study published 8 September in Nature Communications.
Spectrum: Autism Research News
Tag: brain size
Deletion and duplication of the 16p11.2 chromosomal region have opposite effects on brain size, but produce similar alterations in the brain’s processing of sound. Researchers reported these and other unpublished findings at the 2013 Society for Neuroscience annual meeting in San Diego, painting a complex picture of the region’s role in autism.
Social difficulties and early overgrowth of the brain are trademarks of autism, yet a direct connection between the two has been elusive. One group of researchers may have found a link between the two symptoms and a way to treat both at once, they reported Sunday at the 2013 Society for Neuroscience annual meeting in San Diego.
Two studies published 9 July bolster the hypothesis that immune molecules in a pregnant woman’s bloodstream may sometimes cause autism in her child.
Infants who go on to develop autism have excess fluid between the top of the brain and the skull that persists from about 6 months to 2 years of age, according to a study published 9 July in Brain.
Children with autism and their unaffected twins have heads that are significantly larger than average, according to a study published 16 January in the Journal of Autism and Developmental Disorders.
Young boys with fragile X syndrome or autism have larger brains overall than controls do, but the two groups show enlargement of different parts of the brain, according to an imaging study published in September in the Journal of the American Academy of Child and Adolescent Psychiatry.