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Spectrum: Autism Research News

Tag: brain size

January 2012
Three brown mice in a restricted space in a lab experiment..

Cognition and behavior: Mouse models human Rett mutation

by  /  3 January 2012

A mouse model of Rett syndrome that mimics a mutation seen in people shows many features of the disorder, such as hand clasping, according to a study published 27 November in Nature Neuroscience.

December 2011

Study links brain size to regressive autism

by  /  12 December 2011

Larger brains may be associated with regressive autism, but only in boys, according to a study published online 28 November in the Proceedings of the National Academy of Sciences.

November 2011

Clinical research: Toddlers with autism larger than peers

by  /  23 November 2011

Toddlers with autism who have larger-than-normal heads are also taller and weigh more than controls, according to a study published in October in Archives of General Psychiatry.


Rett, autism mouse brains mimic human disorders

by  /  17 November 2011

The brains of mice that model Rett syndrome are smaller than normal overall and have differences in specific regions similar to those seen in people with the disorder, according to unpublished research presented Wednesday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.


‘Outlier’ genes expressed differently in people with autism

by  /  13 November 2011

Individuals who have autism show distinct patterns of gene expression in neurological pathways compared with their unaffected siblings, according to unpublished work presented Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.


Autism brains have too many neurons, study suggests

by  /  10 November 2011

Children with autism have an abnormally large number of neurons in the prefrontal cortex, a brain region important for abstract thinking, planning and social behaviors, according to a study published yesterday in the Journal of the American Medical Association.

October 2011

Cognition and behavior: Autism brains similar in girls and boys

by  /  11 October 2011

Girls with autism have more brain matter than do either controls or girls with developmental disabilities. This defect is particularly pronounced in the left superior frontal gyrus, a region in the medial prefrontal cortex that is responsible for higher-order cognitive function.


Dysmorphology as biomarker for the study of autism

by  /  11 October 2011

Individuals who have autism and dysmorphology comprise a distinct subgroup within the disorder, says geneticist Judith Miles. 

September 2011

Researchers identify gene regulating amygdala volume

by  /  13 September 2011

A variant of the FGF14 gene may decrease the volume of the amygdala, a brain structure needed to interpret emotions in facial expressions, according to results presented on Sunday at the World Congress of Psychiatric Genetics in Washington, D.C.

July 2011

Genetics: Neurexin 1 variant affects volume of healthy brains

by  /  29 July 2011

A variant of neurexin 1, a gene linked to both autism and schizophrenia, is associated with less brain matter than normal in healthy individuals, according to a study published 8 June in PLoS ONE.