A mouse model of Rett syndrome that mimics a mutation seen in people shows many features of the disorder, such as hand clasping, according to a study published 27 November in Nature Neuroscience.
Spectrum: Autism Research News
Tag: brain size
Toddlers with autism who have larger-than-normal heads are also taller and weigh more than controls, according to a study published in October in Archives of General Psychiatry.
The brains of mice that model Rett syndrome are smaller than normal overall and have differences in specific regions similar to those seen in people with the disorder, according to unpublished research presented Wednesday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.
Individuals who have autism show distinct patterns of gene expression in neurological pathways compared with their unaffected siblings, according to unpublished work presented Saturday at the 2011 Society for Neuroscience annual meeting in Washington, D.C.
Children with autism have an abnormally large number of neurons in the prefrontal cortex, a brain region important for abstract thinking, planning and social behaviors, according to a study published yesterday in the Journal of the American Medical Association.
Girls with autism have more brain matter than do either controls or girls with developmental disabilities. This defect is particularly pronounced in the left superior frontal gyrus, a region in the medial prefrontal cortex that is responsible for higher-order cognitive function.
Individuals who have autism and dysmorphology comprise a distinct subgroup within the disorder, says geneticist Judith Miles.
A variant of the FGF14 gene may decrease the volume of the amygdala, a brain structure needed to interpret emotions in facial expressions, according to results presented on Sunday at the World Congress of Psychiatric Genetics in Washington, D.C.
A variant of neurexin 1, a gene linked to both autism and schizophrenia, is associated with less brain matter than normal in healthy individuals, according to a study published 8 June in PLoS ONE.