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Spectrum: Autism Research News

Tag: brain size

October 2012

Molecular mechanisms: Immune molecule boosts brain size

by  /  23 October 2012

Mice with elevated levels of the immune molecule interleukin-6 have abnormally large brains, according to a study published 23 August in the International Journal of Neuroscience.

July 2012

Maternal antibodies may affect brain size in autism

by  /  12 July 2012

The action of certain maternal antibodies on the fetal brain may underlie the large brain size seen in some children with autism, according to preliminary findings from both monkey and human studies presented at a conference in Boston last week.

May 2012

Autism gene PTEN plays vital role in neural stem cells

by  /  31 May 2012

Knocking out an autism-linked gene called PTEN only in neural stem cells of the hippocampus, a brain region central to learning and memory, throws the development of new neurons off course in adult mice, according to research published last month in the Journal of Neuroscience.


Fish study links chromosome 16 genes to head size

by  /  17 May 2012

By creating genetically engineered fish, two independent groups have identified genes in an autism hotspot on chromosome 16 that influence head size and brain development. 


Cognition and behavior: Autism, antisocial brains differ

by  /  1 May 2012

Autism and antisocial disorder are separate conditions, with distinct differences in underlying brain structure, according to a neuroimaging study of the general population. The results were published 4 April in The Journal of Neuroscience.

April 2012
Yellow brain rests on green background with radiating dot pattern.

Clinical research: Study suggests four autism subgroups

by  /  25 April 2012

Individuals with autism may belong to one of four groups with discrete sets of symptoms, the most distinct of which includes immune system abnormalities accompanied by sleep problems and sensory sensitivity. The results were published in the April issue of Autism Research.


Gene expression altered in postmortem autism brains

by  /  23 April 2012

Postmortem brain tissue from people with autism shows differences in the expression of genes involved in a number of molecular pathways, including those that control cortical patterning, programmed cell death and differentiation, according to research published last month in PLoS Genetics.


Giant imaging study identifies genes that govern brain size

by  /  19 April 2012

The largest brain imaging study ever performed has identified candidate genes that influence brain size and general intelligence, according to research published 15 April in Nature Genetics.


Cognition and behavior: Corpus callosum smaller in autism

by  /  4 April 2012

Children with autism have a smaller corpus callosum, a bundle of nerve fibers that connects the two hemispheres of the brain, compared with controls, and this difference persists over two years of development, according to a study published 18 February in the Journal of Autism and Developmental Disorders.

March 2012

Cognition and behavior: Brain changes tied to autism severity

by  /  16 March 2012

Adults with autism have regional differences in brain volume in areas that play a role in social behavior and communication compared with controls, according to a large study published in the February issue of Archives of General Psychiatry. The differences correlate with the severity of autism symptoms, the study also shows.