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Spectrum: Autism Research News

Tag: brain size

April 2012

Gene expression altered in postmortem autism brains

by  /  23 April 2012

Postmortem brain tissue from people with autism shows differences in the expression of genes involved in a number of molecular pathways, including those that control cortical patterning, programmed cell death and differentiation, according to research published last month in PLoS Genetics.

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Giant imaging study identifies genes that govern brain size

by  /  19 April 2012

The largest brain imaging study ever performed has identified candidate genes that influence brain size and general intelligence, according to research published 15 April in Nature Genetics.

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Cognition and behavior: Corpus callosum smaller in autism

by  /  4 April 2012

Children with autism have a smaller corpus callosum, a bundle of nerve fibers that connects the two hemispheres of the brain, compared with controls, and this difference persists over two years of development, according to a study published 18 February in the Journal of Autism and Developmental Disorders.

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March 2012

Cognition and behavior: Brain changes tied to autism severity

by  /  16 March 2012

Adults with autism have regional differences in brain volume in areas that play a role in social behavior and communication compared with controls, according to a large study published in the February issue of Archives of General Psychiatry. The differences correlate with the severity of autism symptoms, the study also shows.

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Autism mutations lead to scores of symptoms in rodents

by  /  14 March 2012

Mutations in more than 100 autism-associated genes lead to shared neurobiological deficits in mice, including alterations in the shape of their brains and changes to the electrical properties of neurons, according to a study published 20 February in Molecular Autism.

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RAS pathway, a potentially unifying theory of autism

by  /  13 March 2012

Dysregulation of the intracellular signaling pathway RAS, a risk factor for idiopathic autism, may provide a unifying theory of the disorder. Although this is not an altogether new hypothesis, several new findings have strengthened the evidence for it considerably.

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February 2012

Cognition and behavior: Asperger brains similar across sexes

by  /  8 February 2012

The brains of men and women with Asperger syndrome are more similar than are those of male and female controls, according to a study published in the January issue of the American Journal of Neuroradiology. The results lend support to the ‘extreme male brain’ theory of autism, the researchers say.

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Insights for autism from attention deficit hyperactivity disorder

by  /  7 February 2012

Autism and attention deficit hyperactivity disorder show genetic and neurobiological overlap, which may provide clues to the origin of both disorders, says Joel Nigg.

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January 2012

Cognition and behavior: Brain scans yield few signs of autism

by  /  31 January 2012

The results of two new studies support recommendations against the use of brain scans to diagnose autism.

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Scanning during sleep effective across autism spectrum

by  /  26 January 2012

Scanning children’s brains while they sleep is a viable alternative to sedation for infants and toddlers across the entire autism spectrum, according to a study published in the January issue of the Archives of General Psychiatry.

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