By creating an atlas of 39 different areas in the mouse cerebellum, researchers have highlighted differences in this region in three mouse models of autism, they reported 22 October in Autism Research.
The branching patterns of excitatory neurons in people with Williams syndrome are roughly the opposite of the patterns seen normally, according to unpublished results from a small study presented Monday at the 2013 Society for Neuroscience annual meeting in San Diego.
Researchers have produced images of connectivity during resting-state activation, which occurs while individuals are resting quietly in a scanner, in mouse brains. The new technique was presented Monday at the 2013 Society for Neuroscience annual meeting in San Diego.
One of the largest genome-wide screens of methyl tags in postmortem brains has found that people with autism have three unique regions of methylation — chemical modifications that affect gene expression. The results were reported 3 September in Molecular Psychiatry.
Researchers have debuted the most comprehensive map to date showing how the suite of methyl tags on the DNA of brain cells changes across the genome over a lifetime. The map, published 4 July in Science, suggests that shifting patterns of methylation may guide key periods of brain development.
A new three-dimensional, whole-brain model provides an unprecedented level of detail of the brain and its connections. Can it be used to study autism?
Researchers have sliced a human brain into more than 7,400 slivers, and stained and scanned them to create ‘BigBrain,’ the most detailed three-dimensional map of a human brain to date, they reported 21 June in Science.
New techniques to scan the brain can produce exquisitely detailed views of white matter, which contains the long cellular fibers that connect neurons. Many of the advances are emerging from the Human Connectome Project, a five-year push to map the brain’s wiring.
Three new studies published in March suggest that some infants who have a high risk of developing autism show early differences in brain responses to sight and sound.
Researchers have cataloged thousands of DNA regions that may act as enhancers — regulating gene expression from afar — in the developing mouse and human brains, according to a study published 14 February in Cell.