Brain-surgery-free probes can record single-neuron activity
The new devices, which monitor neural activity from within blood vessels, show long-term stability in rats and could one day deliver electrical stimulation.
The new devices, which monitor neural activity from within blood vessels, show long-term stability in rats and could one day deliver electrical stimulation.
The map, by far the largest one of an entire brain to date, contains 130,000 neurons and 53 million synapses.
When combined with tissue-inflation methods, the microscope can image axons without the need for tissue slicing, the researchers say.
The new resource aims to aid reproducibility in imaging research.
The work identifies new varieties and may help researchers develop tools to genetically target specific classes of cells.
The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities.
The map diagrams more than half a million neuronal connections in the first complete connectome of Drosophila and holds clues about which brain architectures best support learning.
The finding calls into question differences between autistic and non-autistic people on a decades-old theory-of-mind test involving interacting geometric shapes.
Findings on microglia and other brain cell types bolster the animal’s validity as a model system for the condition.
The open-source software makes it possible to overlay disparate datasets and potentially accelerate hypothesis generation.