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Spectrum: Autism Research News

Tag: brain imaging

May 2022
Color-coded brain images showing reduced thickness of superior frontal gyrus and other regions associated with presence of increased levels of inflammatory moleucle IL-6.

Inflammation may reshape brain regions tied to autism

by  /  6 May 2022

Having a genetic predisposition to inflammation is linked to structural changes in brain regions implicated in neurodevelopmental conditions.

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April 2022

Miniature microscope records thousands of neurons in moving mice

by  /  12 April 2022

The open-source device achieves subcellular resolution in a larger tissue volume than was possible with prior miniscopes, without impinging upon a mouse’s behavior.

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Biases skew behavioral predictions from brain scans

by  /  6 April 2022

Models trained on datasets that lack racial and ethnic diversity perform less accurately on brain scans from Black Americans than their white counterparts.

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: An ineffective therapy and an effective biomarker

by  /  6 April 2022

In this edition, a strategy to help autistic children adapt their skills to new situations shows no benefit, but an early-life autism biomarker does.

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March 2022
Four 3D brains showing areas highlighted in green and purple.

Power shortages dim results of many neuroimaging studies

by  /  16 March 2022

An overreliance on small studies with limited reproducibility has slowed the advancement of neuroimaging, a new analysis suggests.

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February 2022

Amygdala development diverges in autism-specific anxiety

by  /  24 February 2022

The brain region, which is involved in fear and emotion processing, develops differently in autistic children with anxiety than in those without anxiety or in non-autistic children; its development also depends on the type of anxiety a child experiences.

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Cerebellum size shows tenuous genetic link to autism

by  /  21 February 2022

Some genomic areas that help determine cerebellar size are associated with autism, schizophrenia and bipolar disorder, according to a new study. But heritable variants across the genome that also influence cerebellar size are not.

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Dr. Hollis Cline at her desk.

Hollis Cline: Leapfrogging over gaps in autism research

by  /  1 February 2022

A basic scientist at heart, Hollis Cline has spent decades pushing the boundaries of what researchers can see in the brain. Her persistence has led to a deeper understanding of how some autism-linked genes influence brain development.

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October 2021

‘Light beads’ method images activity across the mouse brain

by  /  12 October 2021

The new technique can record hundreds of thousands of neurons firing nearly simultaneously across big swaths of brain tissue in living mice.

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How traits relate to brain activity may differ between autistic boys, girls

by  /  11 October 2021

Scientists should heed these differences when considering resting-state brain activity as a biomarker for autism, the researchers say.

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