Autism researchers are sharpening their statistical tools to make sense of the growing pool of autism genes.
Small pieces of DNA within genes, dubbed ‘microexons,’ are abnormally regulated in people with autism, suggests a study of postmortem brains.
It’s no easy feat to whittle down the list of the most influential autism papers to a mere 10. So please consider this but a taste of the burgeoning field, presented in chronological order and based on suggestions from many researchers.
An analysis of genes expressed in the postmortem brains of people with autism has identified three molecular pathways linked to the disorder. The findings, published 10 December in Nature Communications, add to mounting evidence that the myriad causes of autism converge on common biological processes.
Researchers have for the first time isolated and characterized protein complexes found at the points of connection between neurons. Mutations in some of these proteins are linked to autism.
A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.
Methyl tags on DNA are distributed differently in postmortem brains from people with autism than in control brains, and mouse pups can inherit altered methylation from their older fathers, report two new studies.
Disorganized patches found in the brains of children with autism prompt debate about their significance for the disorder. Three experts give their perspectives.