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Spectrum: Autism Research News

Tag: biomarkers

November 2021
Dr. Shafali Jeste portrait with a vibrant fuschia background.

Shafali Jeste: Early autism meets its match

by  /  30 November 2021

Shafali Jeste has spent the bulk of her scientific career searching for biological markers of autism. Her goal: to improve lives through early diagnosis and speedy testing of therapies.

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Photo: A scientist wearing a green shirt and white gloves holds two black laboratory mice. The viewer is looking over the scientist's shoulder at their cupped hands holding the mice.

Sex bias emerges in new mouse model with autism-linked mutation

by  /  3 November 2021

Compared with a previous mouse strain, a new model better reflects some of the difficulties that people with a rare autism-related syndrome experience, and may help identify biomarkers of the syndrome.

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October 2021

Deep-learning model may accurately predict autism diagnosis

by  /  28 October 2021

The algorithm estimates a child’s likelihood of having autism from patterns of co-occurring conditions in electronic health records, outperforming a widely used screening test.

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How traits relate to brain activity may differ between autistic boys, girls

by  /  11 October 2021

Scientists should heed these differences when considering resting-state brain activity as a biomarker for autism, the researchers say.

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Annimation of eye tracking application following the pupil in a man's eye.

Web app tracks pupil size in people, mice

by  /  8 October 2021

The app relies on artificial intelligence and could help researchers standardize studies of pupil differences in autistic people and in mouse models of autism.

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Closeup photo of a liquid being poured out of a brown bottle.

French pharma firms terminate trials of bumetanide for autism

by  /  1 October 2021

Preliminary results suggested the treatment is no better than placebo at reducing the severity of core autism traits.

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September 2021
Many people in different areas on a target.

Finding a path forward for fragile X drugs

by  /  23 September 2021

The stubborn lack of treatments for fragile X syndrome — a leading cause of inherited intellectual disability and autism — is spurring researchers to revise clinical trial techniques and revisit old drug candidates.

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August 2021
Close-up profile of child with focus on eye.

Visual response shows promise as biomarker in autism-linked condition

by  /  23 August 2021

Brain responses to visual stimuli are smaller and weaker in children with Phelan-McDermid syndrome, an autism-linked genetic condition, than in non-autistic children.

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Image shows two young girls, identical twins, covering their faces with leaves while facing each other.

Q&A with John Constantino: Solving the biomarker conundrum

by  /  3 August 2021

Biological factors that reflect autism’s roots may differ from those that influence how severe the condition is. Failure to make a distinction has stymied the search for biomarkers.

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June 2021
Illustration of transporter mice in brain maze

After 60 years, scientists are still trying to crack a mysterious serotonin-autism link

by  /  4 June 2021

The high levels of serotonin seen in the blood of some autistic people have confounded scientists for more than half a century. Despite so little progress, some researchers refuse to give up.

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