Tag: BDNF

November 2016
News

Growth factor levels may be elevated in children with autism

by  /  11 November 2016

Children with autism may have increased blood levels of brain-derived neurotrophic factor, a protein that spurs the formation of neuronal connections.

1 Comment
October 2015
News

Lab gearing up to screen candidate drugs for Rett syndrome

by  /  21 October 2015

Researchers have established a battery of robust rodent assays to screen treatments for Rett syndrome.

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November 2014
News

Growth factor rescues neurons made from boys with Rett

by  /  18 November 2014

Neurons derived from the skin cells of boys with Rett syndrome can help screen potential treatments for the disorder, suggest unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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April 2014
Opinion / Viewpoint

The case for using ‘prebiotics’

by ,  /  1 April 2014

Prebiotics — nutrients that promote the growth of some beneficial gut bacteria — can influence brain chemistry and behavior. New findings suggest prebiotics as treatments for people with neurological disorders, say Sarkis Mazmanian and Gil Sharon.

1 Comment
March 2014
Opinion / Viewpoint

No longer junk: Role of long noncoding RNAs in autism risk

by ,  /  4 March 2014

Long pieces of RNA that do not code for protein have diverse and important roles in the cell and may contribute to autism risk, say Nikolaos Mellios and Mriganka Sur.

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December 2013
News

Molecular mechanisms: Rett gene boosts protein production

by  /  3 December 2013

MeCP2, the protein mutated in Rett syndrome, is normally responsible for boosting the expression of a large number of genes. This finding, published 3 October in Cell Stem Cell, may explain why growth factors that promote protein production are able to reverse features of the syndrome in mice.

1 Comment
November 2013
News

Existing drugs could treat Rett syndrome, studies suggest

by  /  13 November 2013

Rett syndrome affects many cellular pathways, but correcting just one of these with drugs approved for other purposes may be enough to alleviate symptoms of the disorder. This was the message from two presentations Tuesday at the 2013 Society for Neuroscience annual meeting in San Diego.

6 Comments
October 2013
News

Molecular mechanisms: Study ties growth factor to autism

by  /  22 October 2013

Mutations in the autism-linked protein NHE6 may block the development of neuronal junctions by interfering with a growth factor called BDNF, according to a study published 2 October in Neuron.

1 Comment
May 2012
Opinion

Shrinking brains

by  /  18 May 2012

Long-term treatment with antipsychotic drugs and mood stabilizers can change the structure of the brain.

3 Comments
News

Molecular mechanisms: Growth factor altered in autism brains

by  /  8 May 2012

The brains of individuals with autism have higher-than-typical levels of the precursor to a neuronal growth factor called BDNF, according to a study published in the April issue of the Journal of Neuropathology and Experimental Neurology. The results suggest a mechanism for altered brain development in autism.

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