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Spectrum: Autism Research News

Tag: axons

April 2021
Brains scans reveal sharper boundaries between white and gray matter in autistic people.

Thin insulation may explain atypical cortical thickness seen in autism

by  /  23 April 2021

Differences in myelin, the insulation that surrounds neuronal projections, may shade measurements of cortical thickness on brain scans, a new study suggests.

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March 2021
Oligodendrocyte shown orange on black in this scanning electron micrograph.

How oligodendrocytes may shape autism

by  /  15 March 2021

A growing body of evidence shows that brain cells called oligodendrocytes may play a larger role in autism than previously thought.

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January 2021

Method may improve safety of gene therapies targeting the brain

by  /  28 January 2021

A new approach for delivering gene therapy to the brain reduces nerve damage in primates and could help make gene therapies for conditions related to autism safer.

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computational neural network in red and blue lines.

Computational technique recapitulates neuron shapes

by  /  11 January 2021

A new method automatically reconstructs the 3D branching shapes of neurons from images.

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January 2020
group of six brain images from children show white matter, anomalies shown in red areas

Structure of brain matter in young autistic children may show distinct patterns

by  /  30 January 2020

The long fibers of neurons in the brains of young children with autism are structured differently from those of their neurotypical peers — and from those of older children with the condition.

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November 2019
Micrograph of mouse brain showing transplanted human microglia

Chimeric mouse model aids study of brain’s immune cells

by  /  15 November 2019

A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.

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October 2019
Neurons inside mouse brain are highlighted in a 3D view

New database tracks more than a thousand mouse neurons

by  /  25 October 2019

A new resource that traces individual neurons in the mouse brain may reveal how distant brain regions communicate.

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August 2019

Mice reveal how top autism gene may disrupt brain structure

by  /  26 August 2019

Mutations in an autism gene called ANK2 may alter brain wiring by causing the growth of excess neuronal connections.

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June 2019
Two organoids connected by nerve fibers

In new device, brain organoids ‘talk’ to each other

by  /  14 June 2019

A novel cell culture device enables researchers to grow bundles of nerve fibers from stem cells, mimicking the tissue that connects distant parts of the brain.

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Mouse neurons in a grid show differences

Autism mutation may disrupt brain structure by disabling mitochondria

by  /  13 June 2019

Mice that lack a segment of chromosome 22 — a mutation associated with autism — have unusually sparse connections between brain regions.

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