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Spectrum: Autism Research News

Tag: arbaclofen

June 2023
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Going on Trial: Gene therapy for Rett; return to arbaclofen

by  /  29 June 2023

This month’s newsletter looks at the early safety data from the first gene therapy trial for Rett syndrome, among other drug development news.

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Still from research video of mice socializing.

Multi-lab study hints at benefits of long-tested autism drug

by  /  8 June 2023

The results lend support for clinical trials of arbaclofen in people with an autism-linked condition, the researchers say.

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May 2023
Jeremy Veenstra-VanderWeele looks directly into the camera with a calm expression in a close up shot.

Swings and misses with Jeremy Veenstra-VanderWeele

by  /  30 May 2023

A careful clinician who prizes evidence, Jeremy Veenstra-VanderWeele is happy to embrace trial failures, as long as he learns from them.

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Arbaclofen results; another oxytocin edition

by  /  17 May 2023

New data from clinical trials of arbaclofen and oxytocin underscore the murkiness of null results. Plus, researchers seek clarity on the neurodevelopmental effects of oxytocin during childbirth.

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Photograph of white pills and blister pack on blue pastel colored background.

Trials of arbaclofen for autism yield mixed results

by  /  5 May 2023

Autistic children taking the drug showed improvements in some behaviors but not in their social skills.

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January 2023
A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdoses

by  /  25 January 2023

Going on Trial rounds up new developments in autism-related drug trials. This month we’re revisiting decade-old data from a trial of arbaclofen for fragile X syndrome and looking into a new implant-based approach to quelling seizures, among other treatment strategies.

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January 2022
Visual stimulus of 4 circles with black and white stripes.

Visual task flags autistic people who respond to GABA agonists

by  /  5 January 2022

The investigational drug arbaclofen makes autistic people’s brains respond to a visual task more like non-autistic people’s brains do.

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May 2021

Autism-related conditions linked to altered visual perception

by  /  5 May 2021

A test of binocular rivalry may distinguish between autism subtypes and help researchers screen the efficacy of certain drugs.

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February 2019

Brain’s prefrontal cortex conducts symphony of social players

by  /  20 February 2019

A brain region that orchestrates responses to social cues and aids decision-making may be off tempo in autism.

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October 2018

Study calls into question chemical messenger’s role in autism

by  /  29 October 2018

New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.

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