Connections between 13 autism-linked proteins and their binding partners in excitatory neurons implicate a new molecular pathway.
Spectrum: Autism Research News
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.
Activity patterns of neuronal networks link different genetic subtypes of autism that have similar traits, according to new unpublished research.
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.
Mutations in an autism gene called ANK2 may alter brain wiring by causing the growth of excess neuronal connections.
The largest autism sequencing study to date implicates 99 genes in the condition — but nearly half have a tighter link to intellectual disability or developmental delay.
As the list of autism candidate genes grows, some mouse models of the genes turn up in long-forgotten studies.
Decoding distortions in the brain’s largest nerve tract could lay bare basic problems with long-range neural connections in autism.