Alterations in inhibitory circuits and difficulties in social recognition characterize mice missing one copy of DYRK1A, a gene linked to autism.
Spectrum: Autism Research News
Tag: animal models
After 10 years of work, Neurona may have the data to quiet its skeptics. But its ongoing clinical trial will be the ultimate test.
Increasing or reducing the levels of the UBE3A gene, which is associated with autism and autism-related syndromes, results in altered patterns of synaptic pruning — a process that snips away brain cell connections.
A new tool could help decipher the brain circuits underlying aversion to social touch, which is common in people with autism.
Voles reared primarily by their fathers show altered synapse density.
The findings in rhesus macaque monkeys may provide clues to sex differences in the heredity of social behavior in people.
The new devices, which monitor neural activity from within blood vessels, show long-term stability in rats and could one day deliver electrical stimulation.
The map, by far the largest one of an entire brain to date, contains 130,000 neurons and 53 million synapses.