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Tag: Angelman syndrome

April 2015
News / Toolbox

Tiny square rafts help neurons thrive in lab

by  /  8 April 2015

A convoy of miniature plastic rafts boosts the survival of lab-grown neurons, using a new method that could help autism researchers easily grow many thousands of cells at once.

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March 2015
News

Repurposed drugs may treat Angelman syndrome

by  /  19 March 2015

An acne drug, a dietary supplement and a failed sleeping aid each show promise for Angelman syndrome, according to unpublished results presented Tuesday at a meeting.

2 Comments
January 2015
News

Tweak to molecular scissors cuts path to turn on genes

by  /  26 January 2015

A new technique allows scientists to turn on the expression of any gene, giving them the unprecedented ability to explore the function of every gene in the human genome.

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December 2014
News

Snippets of RNA may reverse symptoms of Angelman syndrome

by  /  4 December 2014

Small pieces of RNA restore the expression of a key gene missing in Angelman syndrome and offer the promise of a highly specific cure, researchers reported Monday in Nature.

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November 2014
News

Feisty mice may reveal autism gene’s link to aggression

by  /  20 November 2014

Varying the number of copies of a single autism-linked gene modulates social behavior and aggression in mice, according to unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

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October 2014
News

Seizures trigger autism-like behaviors in mice

by  /  23 October 2014

Mice with an extra copy of the autism-linked gene UBE3A show abnormal social behavior after experiencing recurrent seizures. The findings, presented Tuesday at the Autism Consortium Research Symposium in Boston, provide one possible explanation for why seizures and autism often go hand in hand.

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September 2014
News

Rousing silenced X chromosome may treat Rett syndrome

by  /  29 September 2014

Drugs that activate the silent copy of the X chromosome in women may be able to undo the damage from mutations in genes located there. The study, published 2 September in Proceedings of the National Academy of Sciences, offers hope for treating Rett syndrome and other disorders linked to the chromosome.

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Opinion / Q&A

Questions for Lawrence Reiter: Extracting clues from teeth

by  /  9 September 2014

Neurologist Lawrence Reiter is growing neurons from the discarded teeth of children with neurological syndromes. Here he describes how dental pulp may help researchers find the genes and pathways that underlie autism symptoms.

4 Comments
August 2014
News

Treatments for Angelman syndrome face critical window

by  /  15 August 2014

Drugs designed to treat Angelman syndrome may alleviate symptoms only if given during a ‘critical period’ early in development. That’s the upshot from unpublished results presented yesterday at a conference in Boston.

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May 2014
News

Clinical research: Angelman gene variants alter symptoms

by  /  30 May 2014

The nature of the mutation that leads to Angelman syndrome — a disorder characterized by speech impairment and developmental delays — affects the disorder’s presentation, reports a study published 19 March in Research in Developmental Disabilities.

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