Tag: AGRE

December 2011
News

Molecular mechanisms: Protein linked to autism-like behavior

by  /  9 December 2011

HMGN1, a protein that regulates gene expression, leads to social deficits and hyperactivity when expressed at elevated levels in mice, according to a study published 9 December in the Journal of Biological Chemistry. This effect may result from HMGN1 dampening MeCP2 expression, the study suggests.

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November 2011
Opinion

Wholesale genomes

by  /  22 November 2011

In October, the autism science and advocacy organization Autism Speaks announced its plans to sequence whole genomes of 10,000 children with the disorder and their family members over the next two years.

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October 2011
News

Machine-learning tool offers rapid autism diagnosis

by  /  27 October 2011

A five-minute online questionnaire can diagnose autism with as much accuracy as the so-called gold standard diagnostic tests, according to unpublished findings presented Tuesday at the Autism Consortium 2011 symposium in Boston.

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News

Later-born children at higher risk for autism

by  /  24 October 2011

In families that have more than one child with autism, the middle children, particularly those born second, have a higher risk of developing autism than other children in the family, according to a study published 19 October in PLoS One. In families that have only one child with autism, however, risk of the disorder rises with each additional birth, the study found.

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September 2011
News

Genetics: Protein that regulates serotonin linked to autism

by  /  27 September 2011

A protein that regulates the development of serotonin-producing neurons in the brain is associated with autism.

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News

Clinical research: Autism categories are not clear-cut

by  /  6 September 2011

Collapsing the three core domains of autism — impairments in social interaction, communication deficits, and repetitive and restricted behaviors — into two makes no difference in the accuracy of diagnosis, according to a statistical analysis published 20 August in the Journal of Autism and Developmental Disorders.

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February 2011
News

Search for Asperger syndrome genes unearths links to autism

by  /  10 February 2011

A genome-wide association study has identified risk factors for Asperger syndrome, some of which overlap with chromosomal regions implicated in autism, according to a study in the December issue of Autism Research.

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November 2010
News

Autism symptoms more severe in younger siblings

by  /  17 November 2010

In families with more than one child diagnosed with autism, younger siblings appear to be more severely affected by the disorder, according to new data presented Tuesday at the Society for Neuroscience annual meeting in San Diego.

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News

Brain ‘transcriptome’ reveals gene networks for autism

by  /  16 November 2010

Scientists have pinpointed two major gene networks relevant to autism by analyzing gene expression in brain tissue from individuals with the disorder. Researchers presented the data Sunday at the Society for Neuroscience annual meeting in San Diego.

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News

Decoding the exome points to new autism genes

by  /  16 November 2010

Sequencing the exomes — regions of the genome that code for proteins — of 18 individuals with autism has revealed new candidate genes for the disorder, researchers reported Sunday at the Society for Neuroscience annual meeting in San Diego.

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