Skip to main content

Spectrum: Autism Research News

Tag: ADNP

January 2023
A hand reaches from above to add a pill to a stack that is resting against the x-axis of a graph.

Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdoses

by  /  25 January 2023

Going on Trial rounds up new developments in autism-related drug trials. This month we’re revisiting decade-old data from a trial of arbaclofen for fragile X syndrome and looking into a new implant-based approach to quelling seizures, among other treatment strategies.

Comments
June 2022

Two top autism-linked proteins connect to build cell ‘skeleton’

by  /  9 June 2022

ADNP and SHANK3 proteins may bind together and alter a neuron’s internal scaffold, hinting at a mechanism that, when disrupted, may underlie several forms of autism.

Comments
January 2022
Normal mouse brain (left) vs brain in mouse lacking POGZ gene (right)

Top autism-linked gene boosts DNA accessibility during development

by  /  10 January 2022

Loss of the POGZ gene in mice makes certain genes inaccessible and prevents their expression.

Comments
November 2021
Photo: A scientist wearing a green shirt and white gloves holds two black laboratory mice. The viewer is looking over the scientist's shoulder at their cupped hands holding the mice.

Sex bias emerges in new mouse model with autism-linked mutation

by  /  3 November 2021

Compared with a previous mouse strain, a new model better reflects some of the difficulties that people with a rare autism-related syndrome experience, and may help identify biomarkers of the syndrome.

Comments
July 2021
Colorful, playful illustrated scene of ewborns on a conveyor belt moving past researchers holding a long, long list.

The push to screen newborns for rare autism-linked genetic conditions

by  /  28 July 2021

As treatments for some autism-linked genetic conditions inch closer to the clinic, researchers are talking more urgently about screening all newborns for such conditions.

Comments
Illustration shows yellow landscape with blue sections and a lot of trains on paths with kids on the trains, going different directions.

Mapping the futures of autistic children

by  /  14 July 2021

Researchers can roughly project what autistic children’s lives will look like years down the road. But how good is their crystal ball — and what are its benefits?

Comments
February 2021

Mutations in frogs point to autism genes’ shared role in neurogenesis

by  /  10 February 2021

Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.

Comments
January 2021

Two top autism genes may have a mechanism in common

by  /  13 January 2021

Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.

Comments
October 2019
Two dark brown research mice

Mice with autism mutation reflect social difficulties seen in people

by  /  21 October 2019

A new autism mouse model carries the same mutation in a gene called ADNP that is seen in autistic people.

Comments
April 2019
children playing at a genetic family group meeting

How families are driving the study of autism genes

by  /  10 April 2019

Parents of children with rare autism-linked mutations are banding together for support and to join forces with scientists, accelerating the pace of research.

Comments