Tag: 16p11.2

August 2019
News

Patterns of DNA tags mark candidate genes for autism

by  /  15 August 2019

Children with autism who carry mutations in the chromosomal region 16p11.2 or the gene CHD8 — two of the leading risk factors for autism — show distinct patterns of chemical tags on their DNA.

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May 2019
A DNA helix showing common and rare variants
News

The multiple hits theory of autism, explained

by  /  1 May 2019

Researchers are studying how a combination of genetic ‘hits’ may contribute to autism’s diversity.

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April 2019
Hands on background of microarray and other genetic information
News

Genetic testing for autism, explained

by  /  10 April 2019

No genetic test can say whether a person has autism, but it may point to a cause for the condition or for any related complications.

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March 2019
News

Deletion, duplication of chromosome 16 segment may confer same autism risk

by  /  6 March 2019

Autism may be just as common among children missing a segment of chromosome 16 as it is in those with an extra copy.

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November 2018
Toddle boy having his head measured in a medical setting.
News

Brain organoid study firmly links autism mutations to RhoA

by  /  7 November 2018

A cellular pathway that helps neurons grow and move during fetal development may drive the changes in head size in some autistic people.

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News

Study links changes in blood flow to autism

by  /  7 November 2018

Mice with an autism-linked deletion in chromosome 16 show abnormalities in their blood vessels and circulation.

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October 2018
Brain cells under magnification glow red, purple and blue.
News

Mini-brains may pin down key genes in large mutations

by  /  22 October 2018

Clusters of brain cells — so-called ‘mini-brains’ grown in the lab — may help researchers understand how large stretches of duplicated or deleted DNA affect the brain.

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Illustration of human brain in brackets suggesting circuit alterations that is associated with certain genetic mutations.
Opinion / Viewpoint

Brain scans of sleeping mice hint at subtypes of autism

by  /  9 October 2018

Mapping the effects of autism mutations on mouse brain circuits may reveal subtypes of the condition in people.

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August 2018
Microscopic images from the eye of a fly.
News

Mutant flies reveal key gene interactions within autism deletion

by  /  20 August 2018

The absence of several interacting genes may underlie the developmental problems seen in people missing a segment of chromosome 16.

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One gray mouse sniffs another in an enclosure.
News

Study revives serotonin as target for autism treatments

by  /  8 August 2018

Boosting the levels of the chemical messenger serotonin makes mice that model autism more social — and brings new hope to a shelved theory in autism.

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