Tag: 16p11.2

November 2018
Toddle boy having his head measured in a medical setting.
News

Brain organoid study firmly links autism mutations to RhoA

by  /  7 November 2018

A cellular pathway that helps neurons grow and move during fetal development may drive the changes in head size in some autistic people.

0 Comments
News

Study links changes in blood flow to autism

by  /  7 November 2018

Mice with an autism-linked deletion in chromosome 16 show abnormalities in their blood vessels and circulation.

0 Comments
October 2018
Brain cells under magnification glow red, purple and blue.
News

Mini-brains may pin down key genes in large mutations

by  /  22 October 2018

Clusters of brain cells — so-called ‘mini-brains’ grown in the lab — may help researchers understand how large stretches of duplicated or deleted DNA affect the brain.

0 Comments
Illustration of human brain in brackets suggesting circuit alterations that is associated with certain genetic mutations.
Opinion / Viewpoint

Brain scans of sleeping mice hint at subtypes of autism

by  /  9 October 2018

Mapping the effects of autism mutations on mouse brain circuits may reveal subtypes of the condition in people.

0 Comments
August 2018
Microscopic images from the eye of a fly.
News

Mutant flies reveal key gene interactions within autism deletion

by  /  20 August 2018

The absence of several interacting genes may underlie the developmental problems seen in people missing a segment of chromosome 16.

0 Comments
One gray mouse sniffs another in an enclosure.
News

Study revives serotonin as target for autism treatments

by  /  8 August 2018

Boosting the levels of the chemical messenger serotonin makes mice that model autism more social — and brings new hope to a shelved theory in autism.

0 Comments
News

Blocking key enzyme eases memory problems, anxiety in autism mice

by  /  1 August 2018

New results implicate an enzyme called ERK in the consequences of missing a segment of chromosome 16.

0 Comments
July 2018
Week of JulyJul
2nd
2018
News / Spotted

Memory shuttle; fly eyes; gaze avoidance and more

by  /  6 July 2018

A protein proves crucial to spatial memory in mice, genes in the 16p11.2 chromosomal region interact in fruit flies’ eye development, and having more autism features tracks with decreased responsiveness to direct gaze.

0 Comments
June 2018
eight brains with various sections highlighted
News

Chromosome 16 deletion miswires brain in people, mice

by  /  12 June 2018

Mice and people missing a copy of a chromosomal region called 16p11.2 show similar patterns of weak brain connections.

0 Comments
News

Chromosome 16’s role in brain, behavior varies by sex

by  /  1 June 2018

Female mice may compensate for the loss of a piece of chromosome 16 better than male mice do.

0 Comments