The results highlight the importance of subgrouping study participants based on their underlying genetics, the researchers say.
Spectrum: Autism Research News
Lumping versus splitting with autism-linked variants: A conversation with Vanessa Vogel-Farley and Yssa DeWoody
Researchers have long studied subgroups of people who share genetic variants, but the newly formed ‘CNV Commission’ is also looking at people with shared traits across different neurodevelopmental conditions.
Scientists have at last filled in the missing gaps — an advance likely to inform every aspect of autism genetics research, Eichler says.
A potential new gene therapy delivered via a single injection mimics ratios of proteins normally found in cells.
These short reports from Spectrum journalists highlight some of the autism-related findings that caught our attention at the meeting this past week.
Children with dup15q syndrome may have telltale patterns of brain activity during sleep and get less non-REM sleep than neurotypical children do.
A collection of rare genetic variants associated with autism and schizophrenia also seem to increase a person’s odds of having attention deficit hyperactivity disorder.
Brain tissues from people with autism of unknown cause and from people with either of two genetic forms of the condition all show similar patterns of methyl groups on DNA.
Mice with extra copies of UBE3A, a gene linked to autism and related conditions, are susceptible to death from seizures.