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Society for Neuroscience 2019

SFN 2019
Coloured transmission electron micrograph (TEM) showing several unmyelinated (green) and myelinated (green with blue border) axons. Schwann cell cytoplasm is red and a nucleus (bottom left) is yellow. The pink lines are the basement membranes.

Loss of insulation on neurons may contribute to autism

by  /  6 March 2020
Genes involved in the formation of myelin, a fatty substance that sheathes neurons, are altered in autistic people and in several mouse models.
SFN 2019

In brain imaging studies of autism, location may alter results

by  /  27 January 2020
A new analysis hints at the source of the rampant inconsistency among brain imaging studies in autism: significant differences among study sites.
SFN 2019
Micrograph of brain organoid in green and red

Spheres of brain cells may offer crystal ball for autism’s origins

by  /  24 January 2020
Researchers have monitored the active genome in brain organoids over the course of nearly two years — and may find clues to autism’s roots.
October 2019
Group of four organoid images
SFN 2019

Mass-produced organoids hint at diversity of autism

by  /  23 October 2019

Researchers have analyzed thousands of brain organoids derived from six autistic people, gaining the potential to rapidly screen drugs.

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Group of images of neurons glow green
SFN 2019

New technique records neuronal teamwork in live mice

by  /  23 October 2019

A new imaging technique detects specific groups of firing neurons in the brains of moving mice, enabling scientists to study brain activity linked to a particular behavior.

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Two male finches sitting on roost in cage.
SFN 2019

Protein linked to autism may help birds learn songs from elders

by  /  23 October 2019

Turning down the expression of a gene linked to autism leaves zebra finches singing disorganized songs.

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UBE3A
SFN 2019

Rat model mimics communication problems in Angelman syndrome

by  /  23 October 2019

Rats missing UBE3A, the gene mutated in people with Angelman syndrome, squeak frequently but tend not to be responsive to the play and squeaks of other rats.

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SFN 2019

Researchers debut mouse model for new autism gene

by  /  23 October 2019

Mice lacking one copy of a gene called DDX3X have developmental delay and sensory, motor and behavioral problems — similar to those seen in people with a mutation in the gene.

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SFN 2019

Sound sensitivity may hinder autistic people’s ability to communicate

by  /  23 October 2019

People with autism process the pitch and emotional tone in speech differently than their neurotypical peers — which may make it harder for them to pick up on nuances of social communication.

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Smart phone with augmented reality app
SFN 2019

Augmented-reality app brings research images to life

by  /  22 October 2019

A new mobile app enhances scientific images by displaying augmented-reality renderings of the complete data over printed figures.

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two neurons on yellow and orange background
SFN 2019

Brain’s sensory relay station may play unexpected role in autism

by  /  22 October 2019

Neurons in a brain region called the thalamus may regulate social behavior and play a key role in autism.

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Marijuana plant
SFN 2019

Cannabis compound improves sociability in autism mouse model

by  /  22 October 2019

A single dose of cannabidiol, a component of marijuana, eases seizures and improves learning and sociability in mice with mutations in an autism gene called CDKL5.

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SFN 2019

Cesarean sections may leave young brains vulnerable to injury

by  /  22 October 2019

Delivery by cesarean section leads to subtle brain and behavioral alterations in mice, particularly those delivered prematurely.

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