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Expert opinions on trends and controversies in autism research.

Previous articles

October 2011
Opinion / Viewpoint

Dysmorphology as biomarker for the study of autism

by  /  11 October 2011

Individuals who have autism and dysmorphology comprise a distinct subgroup within the disorder, says geneticist Judith Miles. 

2 Comments
September 2011
Opinion / Viewpoint

Insights for autism from Charcot-Marie-Tooth disease

by  /  27 September 2011

Charcot-Marie-Tooth disease and autism are both associated with alterations in the number of copies of certain genetic regions, mutations in multiple candidate genes and with both inherited and spontaneous mutations, notes human geneticist James Lupski.

2 Comments
Opinion / Viewpoint

Vision as gateway for understanding autism

by ,  /  8 September 2011

Impairments in vision, even if they don’t cause autism, are likely to be manifestations of underlying neural abnormalities, says Pawan Sinha, professor of vision and founder of the humanitarian organization Project Prakash.  

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August 2011
Opinion / Viewpoint

How fish can help find causes of autism

by ,  /  29 August 2011

Zebrafish share genes and pathways with humans, making them a useful tool to identify the genes that malfunction in autism, says expert Hazel Sive.

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Opinion / Viewpoint

Fair representation for the fairer sex in autism research

by  /  16 August 2011

Including more females in autism research studies will aid the search for genetic and environmental susceptibility factors for the disorder, says genetic psychiatrist Lauren Weiss.

2 Comments
Opinion / Viewpoint

Studying autism genetics in special populations

by  /  2 August 2011

The study of any genetic disorder benefits from including the many diverse human populations in our world, and autism should be no different, says geneticist Christopher Walsh.

1 Comment
July 2011
Opinion / Viewpoint

Insights for autism from Angelman syndrome

by , ,  /  19 July 2011

Deletions or duplications of the UBE3A gene lead to both Angelman syndrome and some cases of autism, respectively. Studying the effects of altered gene dosage in this region will provide insights into brain defects and suggest targets for therapies for both disorders, says expert Benjamin Philpot.

1 Comment
Opinion / Viewpoint

Studying infant sibs of children with autism spectrum disorder

by  /  5 July 2011

Studying the infant siblings of children who have autism to identify early signs of the disorder is expected to have enormous impact on the field from a clinical and a basic science standpoint, says psychologist Karen Dobkins.

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June 2011
Opinion / Viewpoint

Drug trials for fragile X syndrome lead the way for autism

by  /  21 June 2011

Several targeted trials on drugs that treat fragile X syndrome are under way. But accurate endpoints to measure the drugs’ effectiveness are crucial, argues developmental and behavioral pediatrician Randi Hagerman.

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Opinion / Viewpoint

Solving the complex causes of a multi-hit disorder

by ,  /  7 June 2011

What’s known about the genetics of autism supports the ‘snowflake’ hypothesis — that the molecular underpinnings of disease are essentially unique from individual to individual — says human geneticist Brett Abrahams.

1 Comment

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