Clinicians should place children under age 5 who have developmental delay into a broad diagnostic category, called ESSENCE, which may then resolve into any number of individual diagnoses over time, says Christopher Gillberg.
Spectrum: Autism Research News
Expert opinions on trends and controversies in autism research.
Certain mutations may hijack the normal mechanisms of sperm production, leading to an enrichment of mutant sperm in older fathers, and to the paternal-age effect in autism.
The autism-like features seen in related neurological disorders may be the result of intellectual disability and not a shared underlying biology, says Alan Packer.
Emerging evidence indicates that microglia, the brain’s immune cells, are altered in some individuals with autism, raising questions about their role in brain development, says Beth Stevens.
Many children with autism have problems with sleep, which can worsen symptoms of the disorder. A better understanding of sleep in autism may help reveal the mechanisms of autism and point to potential treatments, say Ruth O’Hara and Michelle Primeau.
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