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Expert opinions on trends and controversies in autism research.

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December 2012
Opinion / Viewpoint

Perspective: Brain scans need a rethink

by ,  /  6 December 2012

Head movement can bias brain imaging results, undermining a leading theory on the cause of autism, say Ben Deen and Kevin Pelphrey.

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November 2012
Opinion / Viewpoint

Defining language deficits across autism spectrum

by ,  /  27 November 2012

We are on the verge of a seismic shift in the definition of autism spectrum disorders, says David Skuse. Under proposed guidelines for autism diagnosis, the canard that most people with the disorder cannot speak, or have such disordered language that they cannot sustain a conversation, has been abandoned.

4 Comments
Opinion / Viewpoint

Oxytocin’s power

by  /  13 November 2012

A new study shows that long-term treatment with oxytocin, a hormone that typically enhances social bonds, can have unexpected consequences, says Sue Carter, a research scientist at RTI International.

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Opinion / Viewpoint

Insights for autism from schizophrenia

by ,  /  13 November 2012

Lessons learned from postmortem studies of schizophrenia are applicable to research on autism, a disorder for which brain tissue has not been as well studied, say Allison Curley and David Lewis.

1 Comment
October 2012
Opinion / Viewpoint

Drug zone

by  /  26 October 2012

Rodent and stem cell models remain challenging for developing psychiatric drugs, says Michael Ehlers, chief scientific officer of neuroscience at Pfizer.

1 Comment
Opinion / Viewpoint

Transparent reports

by  /  19 October 2012

New standards for animal studies, including an emphasis on replicating results and the publication of negative findings, are vital for research progress, says Jacqueline Crawley.

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Opinion / Viewpoint

Helpful hurdles

by ,  /  16 October 2012

Rapid progress in gene discovery and an emerging map of the molecular landscape of normal brain development are presenting unprecedented opportunities to unravel the biology of autism spectrum disorders, say Matthew State and Nenad Sestan.

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Opinion / Viewpoint

A call for open-science approaches in autism research

by  /  16 October 2012

Sharing data and tools is universally efficient, but the study of autism in particular presents challenges that can benefit from an open-science framework, says Randy Buckner.

1 Comment
Opinion / Viewpoint

Speedy mice

by  /  2 October 2012

Amphetamines and other compounds with stimulant properties may improve social behaviors in a subset of individuals who have autism with hyperactivity, says Jill Silverman.

0 Comments
Opinion / Viewpoint

Placenta plays potent role in autism risk

by ,  /  2 October 2012

As the central organ regulating maternal-fetal interactions, the placenta is perfectly positioned to mediate environmental and genetic risk factors during prenatal development. It may also relay risk factors for autism to the fetus, says Paul Patterson.

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