Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole
Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.
Conversations with experts about noteworthy topics in autism.
Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.
Collecting brain scans from thousands of people can be challenging in autism research; data-sharing and collaborative efforts can help drive results that stand up to statistical scrutiny.
A new analysis package enables researchers to distill multiple measures of Angelman syndrome mice into a single ‘severity score.’
The pair’s new guidebook offers practical steps to make clinical trials easier and more meaningful for autistic participants.
Non-neuronal brain cells called astrocytes secrete proteins that seem to hamper the growth of neurons in people with autism-related syndromes. These proteins could be new drug targets, Allen says.
Too often, people outside the margins of what’s considered classic autism are left out of research agendas, Abubakare says.
Oxytocin therapies have failed to consistently benefit autistic people, but their effects in people with two autism-linked conditions may yield new insights, experts argue.
The two psychologists share tips to help autism researchers adopt established methods and make their work more transparent and reproducible.
Researchers have long studied subgroups of people who share genetic variants, but the newly formed ‘CNV Commission’ is also looking at people with shared traits across different neurodevelopmental conditions.
Shifts in diagnostic criteria have only added to the condition’s bedeviling heterogeneity, an analysis of smiling, sitting, walking and other early milestones in more than 17,000 autistic children reveals.