Technique decodes gene sequence and activity in single cells
A new method simultaneously reveals a single cell’s DNA sequence and which of its genes are turned on.
Emerging tools and techniques that may advance autism research.
A new method simultaneously reveals a single cell’s DNA sequence and which of its genes are turned on.
A new mathematical method confidently ranks genes based on their likely impact in a disorder. The approach may help researchers home in on important autism genes.
A new method that lets researchers trace the paths of many neurons at once may reveal how neurons go astray in autism.
Inexpensive ‘chips’ imprinted with tiny wells and channels provide a glimpse of neurons communicating in culture.
An online catalog helps clarify the roles of thousands of spontaneous mutations in four neuropsychiatric disorders, including autism.
A new method for labeling cell lines and checking their quality could improve the validity of study results.
A new technique allows researchers to trace the location and measure expression levels of hundreds of genes in individual cells. The method, described 9 April in Science, could reveal networks of genes with relevance to autism.
A convoy of miniature plastic rafts boosts the survival of lab-grown neurons, using a new method that could help autism researchers easily grow many thousands of cells at once.
A 20-minute test enlists parents in gauging a toddler’s social development by showing them a video of how a typically developing child acts.
Newly developed microscopic beads give cells unique barcodes based on the cells’ gene expression patterns. This faster and cheaper system could help researchers study autism in cultured cells.