A new software tool detects chromosomal alterations present in only a subset of cells in the body. This method, described 31 May in BMC Genomics, may help reveal mosaicism’s contribution to neurological disorders.
Emerging tools and techniques that may advance autism research.
A new technique to transform human stem cells into neurons is faster, more efficient and more reliable than existing methods, according to a study published 5 June in Neuron.
By combining bioinformatics techniques with an analysis of gene expression, researchers have identified 30 candidate genes for autism, according to a study published 28 May in Translational Psychiatry.
Screening the genome for small chromosomal abnormalities may identify potential genetic causes of autism or intellectual disability in 16 percent of children tested, according to a study published 24 May in the European Journal of Paediatric Neurology.
To study attention in people with autism during complex social situations, researchers have developed a virtual reality version of public speaking, according to a study published 20 May in Autism Research.
A new statistical method for linking genes to a disorder analyzes both rare and common variants of a gene at the same time, according to a study published 14 May in the American Journal of Human Genetics. This makes it possible to confirm associations that other techniques might overlook.
A new microscopy technique, published in the May issue of Nature Methods, can show the activity of more than 80 percent of the brain’s neurons at one time.
Using high-resolution microscopy, researchers can watch as signaling complexes assemble at neuronal junctions in zebrafish embryos, according to a study published 17 April in Cell Reports.