A basic scientist at heart, Hollis Cline has spent decades pushing the boundaries of what researchers can see in the brain. Her persistence has led to a deeper understanding of how some autism-linked genes influence brain development.

Shafali Jeste has spent the bulk of her scientific career searching for biological markers of autism. Her goal: to improve lives through early diagnosis and speedy testing of therapies.

Brian Lee has transformed the science of linking prenatal experiences to a child’s chances of having autism; his work taps social skills as well as statistical acumen.

A Paris-born child psychiatrist, Fombonne has advanced bold positions on the cause, prevalence and nature of autism during a career spanning four countries.

Over the course of a career spanning more than three decades, Huda Zoghbi has won almost every major biology and neuroscience research award that exists. More than 20 years since she discovered the gene behind Rett syndrome, she remains laser focused on unlocking the condition’s secrets and finding effective treatments.

Elizabeth Berry-Kravis has spent decades uncovering molecular clues to fragile X syndrome and crafting trials of treatments. Her efforts are paying off.

Spectrum spoke with three Black scientists about why they got into autism research, what keeps them excited about their work and how the field could become more diverse.

Even as a small child, geneticist Elise Robinson wondered why people think the way they do. Today, that question informs much of her autism research.

Alysson Muotri aims to build a ‘thinking’ brain as a model for autism — even if his colleagues consider that work controversial.

Damien Fair has a knack for transforming obstacles into opportunities, a trait that has brought trailblazing discoveries and admiration from colleagues.