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Spectrum: Autism Research News

Community Newsletter: Social memory; viral vector for striatum; brain gene expression

by  /  14 May 2023
Speech bubble formed by a network of communication

Illustration by Laurène Boglio

On LinkedIn, Eunji Kong of Columbia University described the second part of her Ph.D. thesis, “Dynamic and stable hippocampal representations of social identity and reward expectation support associative social memory in male mice,” published 5 May in Nature Communications.

Casey Maguire of Harvard University posted a link to his team’s new work, “Increased striatum transduction with an engineered AAV capsid and selective transduction of striatal cholinergic neurons using a truncated human choline acetyltransferase promoter,” published 8 May in Molecular Therapy: Methods & Clinical Development.

Baptiste Lacoste of the University of Ottawa shared a link to his team’s latest study, “16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice,” published 6 May in Cell Reports.

Joshua Dubnau of Stony Brook University and Michael Lombardo of the Istituto Italiano di Tecnologia each posted a Twitter thread describing the preprint “A study of gene expression in the living human brain,” posted 26 April on medRxiv.

“Wow this blows my mind. But indeed, hardly surprising- mRNA profiles of dead brains may not correspond to the same brains when they were alive,“ wrote Christos Proukakis of University College London in a quote tweet.

Richard Bethlehem of Cambridge University shared a link to a study called “Mapping human brain charts cross-sectionally and longitudinally,” published 8 May in PNAS.

Andrew Zalesky of the University of Melbourne, Magdalena Martínez-García of the University of British Columbia, Kuldeep Kumar of the University of Montreal and James Booth of Vanderbilt University all quote tweeted Bethlehem.

That’s it for this week’s Community Newsletter! If you have any suggestions for interesting social posts you saw in the autism research sphere, feel free to send an email to [email protected].

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