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Spectrum: Autism Research News

News Archive

June 2023
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Going on Trial: Gene therapy for Rett; return to arbaclofen

by  /  29 June 2023

This month’s newsletter looks at the early safety data from the first gene therapy trial for Rett syndrome, among other drug development news.

Research image comparing microglia with serotonin receptors to those without.

Serotonin powers pruning of developing brain circuits in mice

by  /  28 June 2023

Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.

Illustration of mitochondria as a kind of Stonehenge, with the shapes standing upright, casting shadows, against a blue sky.

Mitochondria mediate effects of PTEN mutations

by  /  26 June 2023

Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.

Many mouths making conversation, with speech bubbles in red and blue.

Community Newsletter: Nanoscale brain imaging; naturalistic mouse set-ups

by  /  25 June 2023

Our feeds this week were full of discussion about a new super-resolution microscopy method and ways to make mouse behavioral experiments more natural.

A photograph of a mouse against a swirly, multi-colored backdrop

Psychedelics give mice second chance to learn social rewards

by  /  23 June 2023

The drugs may reopen a critical window during development in which the brain can more easily adjust its connections.

Image of three developing axons.

Autism’s ties to the cell skeleton

by  /  22 June 2023

Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.

Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Modified MRI; father findings

by  /  22 June 2023

This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.

Portrait photograph of Donald Triplett against a black background.

Donald Triplett, autism’s ‘Case 1,’ dies at 89

by  /  20 June 2023

Triplett gained media attention for his autism later in life, and he became the face of the effort to research the lives of older adults with autism.

Mice socialize in an enclosure

Neurons in thalamus sort new social cues from familiar ones

by  /  20 June 2023

A subset of thalamic neurons support an aspect of social behavior called social recognition, according to experiments in mice.

Speech bubble formed by a network of communication

Community Newsletter: Sensory sensitivities; neuroscience podcasts

by  /  18 June 2023

Researchers took to social media this week to discuss the mechanisms behind hypersensitivity in autism and share their favorite neuroscience-focused podcasts.