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Spectrum: Autism Research News

News Archive

June 2023
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

Going on Trial: Gene therapy for Rett; return to arbaclofen

by  /  29 June 2023

This month’s newsletter looks at the early safety data from the first gene therapy trial for Rett syndrome, among other drug development news.

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Research image comparing microglia with serotonin receptors to those without.

Serotonin powers pruning of developing brain circuits in mice

by  /  28 June 2023

Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.

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Illustration of mitochondria as a kind of Stonehenge, with the shapes standing upright, casting shadows, against a blue sky.

Mitochondria mediate effects of PTEN mutations

by  /  26 June 2023

Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.

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Many mouths making conversation, with speech bubbles in red and blue.

Community Newsletter: Nanoscale brain imaging; naturalistic mouse set-ups

by  /  25 June 2023

Our feeds this week were full of discussion about a new super-resolution microscopy method and ways to make mouse behavioral experiments more natural.

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A photograph of a mouse against a swirly, multi-colored backdrop

Psychedelics give mice second chance to learn social rewards

by  /  23 June 2023

The drugs may reopen a critical window during development in which the brain can more easily adjust its connections.

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Image of three developing axons.

Autism’s ties to the cell skeleton

by  /  22 June 2023

Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Modified MRI; father findings

by  /  22 June 2023

This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.

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Portrait photograph of Donald Triplett against a black background.

Donald Triplett, autism’s ‘Case 1,’ dies at 89

by  /  20 June 2023

Triplett gained media attention for his autism later in life, and he became the face of the effort to research the lives of older adults with autism.

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Mice socialize in an enclosure

Neurons in thalamus sort new social cues from familiar ones

by  /  20 June 2023

A subset of thalamic neurons support an aspect of social behavior called social recognition, according to experiments in mice.

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Speech bubble formed by a network of communication

Community Newsletter: Sensory sensitivities; neuroscience podcasts

by  /  18 June 2023

Researchers took to social media this week to discuss the mechanisms behind hypersensitivity in autism and share their favorite neuroscience-focused podcasts.

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