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Spectrum: Autism Research News

News Archive

May 2022
Speech bubble formed by a network of communication

Community Newsletter: Ethical review boards, Spectrum 10K, participatory tips

by  /  29 May 2022

The autism science community this week tweeted about whether underpowered studies pose ethical questions, if Spectrum 10K should restart and why autistic advocates participate in biomedical research.

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people stand in as the base pairs in a DNA helix.

Spectrum 10K gets green light from ethics agency

by  /  27 May 2022

After a months-long review, the United Kingdom’s Health Research Authority upheld an earlier ethics approval for the embattled autism genetics study.

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Illustration of a rat in profile with the middle section of its body replaced by a red outline containing small yellow polygons against a navy blue background

Six steps to using machine learning for animal behavior research

by  /  26 May 2022

Machine-learning tools are widely available and can help speed up studies in animal models of autism. Here’s how to get started with the ‘minimal viable product’ and a few pro tips.

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Ultrasound in black and white shows a pattern.

Heart anomalies abound in mouse models of autism

by  /  23 May 2022

Of nine genetic models examined in a new study, all had some incidence of cardiac abnormalities. But the problems varied widely depending on the affected genes.

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Many mouths making conversation, with speech bubbles in red and blue.

Community Newsletter: COVID-19 at INSAR, PTEN enhancer, baby sib findings

by  /  22 May 2022

This week’s newsletter looks at tweets about COVID-19 at last week’s INSAR meeting, an unusual enhancer regulating the autism-linked gene PTEN, and new findings from the Infant Brain Imaging Study.

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A playful chart is made from bars in lively patterns and red and blue.

By the Numbers: Suspensions, unemployment, health checks

by  /  20 May 2022

This edition plots school suspensions and the unemployment gap for autistic people, and charts outcomes for those who attend regular health checks.

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A woman in a white lab coat uses a micropipette

Modified CRISPR tool boosts UBE3A levels in mice

by  /  20 May 2022

A deactivated form of the gene editor restores UBE3A expression in mice and human neurons without cutting the genome. It may hold promise for future Angelman gene therapies.

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Structural brain changes foretell language skills in autistic infants

by ,  /  19 May 2022

Increased white-matter maturation tracks with stronger language abilities later in childhood, but the relationship with cortical thickness is less clear.

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Lab mice (Mus musculus), tribe Balbc, three 13 day old babies with eyes still closed, laying side by side

Sleepy mice with autism-linked mutation struggle to fall asleep

by  /  19 May 2022

Mice with a mutated copy of SHANK3 fail to establish normal sleep patterns during development.

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Researchers publish new dataset on minimally verbal autistic people

by  /  18 May 2022

Researchers at the Massachusetts Institute of Technology published the first repository of vocalizations from minimally verbal autistic people. Those with few or no spoken words still produce a range of phonemes, or units of sound, that may serve as developmental markers or intervention targets.

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